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Alzheimer's Cases to Double by 2060: Report

As the baby boomer population ages, the number of Americans with Alzheimer's disease will double by 2060, researchers report.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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DEMENTIA and stroke risk could be increased by drinking diet soft drinks daily, researchers have claimed. The risk of developing Alzheimer ’s disease increased almost three times compared to those that don’t drink diet fizzy drinks.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: Through team collaboration and engagement of others in the community who work with Latinos with dementia, we believe this process allowed us to successfully create culturally appropriate informational materials that address a sensitive topic for Hispanic/Latino families. CLINICAL IMPLICATIONS: Brain tissue is needed to further knowledge about underlying biological mechanism of neurodegenerative diseases, however it is a sensitive topic. Materials assist with family discussion and facilitate the family's follow-through with BD. PMID: 29227743 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - Category: Geriatrics Tags: Clin Gerontol Source Type: research
AbstractAcetylcholine esterase (AChE) is one of the targeted enzymes in the therapy of important neurodegenerative diseases such as Alzheimer ’s disease. Many studies on carbazole- and oxazolone-based compounds have been conducted in the last decade due to the importance of these compounds. New carbazole-bearing oxazolones were synthesized from several carbazole aldehydes and p-nitrobenzoyl glycine as AChE inhibitors by the Erlenmeyer r eaction in the present study. The inhibitory effects of three carbazole-bearing oxazolone derivatives on AChE were studied in vitro and the experimental results were modeled using art...
Source: Interdisciplinary Sciences, Computational Life Sciences - Category: Bioinformatics Source Type: research
Publication date: 1 April 2018 Source:NeuroImage, Volume 169 Author(s): W. Huizinga, D.H.J. Poot, M.W. Vernooij, G.V. Roshchupkin, E.E. Bron, M.A. Ikram, D. Rueckert, W.J. Niessen, S. Klein Both normal aging and neurodegenerative disorders such as Alzheimer's disease (AD) cause morphological changes of the brain. It is generally difficult to distinguish these two causes of morphological change by visual inspection of magnetic resonance (MR) images. To facilitate making this distinction and thus aid the diagnosis of neurodegenerative disorders, we propose a method for developing a spatio-temporal model of morphological dif...
Source: NeuroImage - Category: Neuroscience Source Type: research
Discussion Dose-dependent and cumulative influence of repetitive mild traumatic brain injury–induced mechanical stress may trigger and/or accelerate neurodegeneration by pushing protein concentration over the disease threshold.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Discussion These findings may provide support for expanding preclinical Tg mouse studies in AD with a TBI weight drop model, insights into the progression of pathological targets, their relations to apoptosis, and timing of interventions against these targets and apoptosis. Such studies may demonstrate the potential for drugs to effectively and safely inhibit preprogrammed cell death as a new drug development strategy for use in the fight to defeat AD.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
Leucadia Therapeutics is a startup company focused on Alzheimer's disease, noteworthy for being one of the few ventures to depart from the orthodoxy of immunotherapy to clear amyloid and tau protein aggregates. The Leucadia founder is working on the establishment of a faster and cheaper path to an effective therapy for Alzheimer's that nonetheless still addresses the deeper causes of the condition. Leaving the mainstream is perhaps more of a challenge in the Alzheimer's research community than elsewhere; the US National Institute on Aging has for years been primarily an Alzheimer's concern, and the biggest of Big Ph...
Source: Fight Aging! - Category: Research Authors: Tags: Healthy Life Extension Community Source Type: blogs
The purpose of this study was to investigate the effect of an 8-week nursing intervention consisting of 2 weekly sessions of music and reminiscence therapy together with the application of reality orientation techniques. Our expectation at the onset of the study was that listening to music that was familiar and connected with the memory of past events would, due to the music's emotional impact, stimulate memory associations, leading, in turn, to a positive effect on depression and anxiety in people living with dementia. We carried out a pre-/posttest intervention design with a sample of 19 patients divided into 2 groups&md...
Source: Holistic Nursing Practice - Category: Nursing Tags: Features Source Type: research
CONCLUSIONS ABCA2 mRNA expression and methylation is associated AD risk. ABCA2 may be used as a biomarker for AD diagnosis and may be a potential therapeutic target of AD. PMID: 29224028 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
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