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Post-therapy lesions in patients with non-Hodgkin’s lymphoma characterized by 18F-FDG PET/CT-guided biopsy using automated robotic biopsy arm

Conclusion 18F-FDG PET/CT for response evaluation in NHL possesses a low PPV and hence warrants histopathological correlation when 18F-FDG PET/CT findings influence management decision. Diagnostic yield of 18F-FDG PET/CT-guided biopsy is high and has the potential to reduce sampling errors.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research

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We describe the case of a 69-year-old man with a thoracic pseudoaneurysm caused by a diffuse large B-cell lymphoma. He had a large mass inside the aortic arch. Five weeks later, an asymptomatic aneurysm protruding from the minor curvature of the distal aortic arch was observed. We suspected a mycotic pseudoaneurysm and performed total arch replacement with an omental pedicle flap graft. Intraoperative tissue cultures and histopathologic tests identified no bacteria, however. Eventually, a pathologic examination revealed that the structure initially suspected to be an intramural thrombus was a diffuse large B-cell lymphoma....
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Conclusion: ADR induced an upregulation of caspase-3, Bax, IL-6, and collagen, as well as a depression in Bcl-2. Thus, apoptosis and fibrosis may play an important role in ADR-induced cardiomyopathy. PMID: 29234360 [PubMed]
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research
MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma, Published online: 15 December 2017; doi:10.1038/s41408-017-0033-8MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma
Source: Blood Cancer Journal - Category: Hematology Authors: Source Type: research
Outcomes of patients with peripheral T-cell lymphoma in first complete remission: data from three tertiary Asian cancer centers, Published online: 15 December 2017; doi:10.1038/s41408-017-0030-yOutcomes of patients with peripheral T-cell lymphoma in first complete remission: data from three tertiary Asian cancer centers
Source: Blood Cancer Journal - Category: Hematology Authors: Source Type: research
We describe the clinicopathologic features of 17 patients who had a hematologic malignancy of various types, were treated, and subsequently developed a lymphoproliferative disorder (LPD). There were 10 men and 7 women with a median age of 59 years (range, 36 to 83 y). The primary hematologic neoplasms included: 5 chronic lymphocytic leukemia/small lymphocytic lymphoma, 3 plasma cell myeloma, 2 acute monoblastic leukemia, and 1 case each of mixed-phenotype acute leukemia, chronic myeloid leukemia, splenic marginal zone lymphoma, follicular lymphoma, mantle cell lymphoma, T-cell prolymphocytic leukemia, and peripheral...
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research
Conclusion: Intravitreal MTX injections and systemic ibrutinib may represent effective treatment options for patients diagnosed with intraocular mantle cell lymphoma.
Source: Retinal Cases and Brief Reports - Category: Opthalmology Tags: Case Report Source Type: research
Conditions:   Advanced Solid Tumor;   Recurrent Solid Tumor;   Lymphoma;   Recurrent Lymphocyte Depleted Classical Hodgkin Lymphoma Intervention:   Biological: GB226 Sponsor:   Genor Biopharma Co., Ltd. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lymphoma;   Myeloma;   Leukemia;   Aplastic Anemia Interventions:   Other: Inspiratory Muscle Training;   Other: Aerobic Training Sponsor:   Daniel Godoy Martinez Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   CD30-Positive Neoplastic Cells Present;   Folliculotropic Mycosis Fungoides;   Recurrent Mycosis Fungoides;   Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma;   Refractory Mycosis Fungoides;   Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma;   Sezary Syndrome Interventions:   Drug: Brentuximab Vedotin;   Drug: Lenalidomide;   Other: Laboratory Biomarker Analysis Sponsor:   City of Hope Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Lymphoma;   Myeloma;   Leukemia;   Aplastic Anemia Interventions:   Other: Inspiratory Muscle Training;   Other: Aerobic Training Sponsor:   Daniel Godoy Martinez Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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