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Lesion Segmentation in Automated 3D Breast Ultrasound: Volumetric Analysis.

Lesion Segmentation in Automated 3D Breast Ultrasound: Volumetric Analysis. Ultrason Imaging. 2017 Nov 01;:161734617737733 Authors: Agarwal R, Diaz O, Lladó X, Gubern-Mérida A, Vilanova JC, Martí R Abstract Mammography is the gold standard screening technique in breast cancer, but it has some limitations for women with dense breasts. In such cases, sonography is usually recommended as an additional imaging technique. A traditional sonogram produces a two-dimensional (2D) visualization of the breast and is highly operator dependent. Automated breast ultrasound (ABUS) has also been proposed to produce a full 3D scan of the breast automatically with reduced operator dependency, facilitating double reading and comparison with past exams. When using ABUS, lesion segmentation and tracking changes over time are challenging tasks, as the three-dimensional (3D) nature of the images makes the analysis difficult and tedious for radiologists. The goal of this work is to develop a semi-automatic framework for breast lesion segmentation in ABUS volumes which is based on the Watershed algorithm. The effect of different de-noising methods on segmentation is studied showing a significant impact ([Formula: see text]) on the performance using a dataset of 28 temporal pairs resulting in a total of 56 ABUS volumes. The volumetric analysis is also used to evaluate the performance of the developed framework. A mean Dice Similarity Coefficient of [Formula: s...
Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research

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Hologic (NSDQ:HOLX) said recently that it won FDA 510(k) clearance for its Quantra 2.2 breast density assessment software and that it inked a development and distribution deal with Clarius Mobile Health for its wireless, handheld ultrasound scanner. The Marlborough, Mass.-based company said the Quantra 2.2 software uses a proprietary algorithm to analyze mammography images for the distribution and texture of breast tissue to produce patient-specific breast density assessments. “As the global leader in breast cancer screening technology, we relentlessly pursue the development of clinically superior products that ...
Source: Mass Device - Category: Medical Devices Authors: Tags: 510(k) Business/Financial News Distribution Food & Drug Administration (FDA) Regulatory/Compliance Ultrasound Women's Health Hologic Source Type: news
The objective of the initiative is to improve the diagnosis accuracy in detecting breast cancer, specifically when reading ultrasound breast scans and mammograms. The project will take place in rural towns, areas where the cancer is common, and regions where medical practitioners are short staffed.According to Xinhuanet,breast cancer is the most malignant tumor found in Chinese females, and there were 272,000 new cases of breast cancer in China in 2015.Through feeding the machine hundreds of scans, the institute hopes it will eventually be able to interpret breast reports. The machine can read a report at lightening speeds...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Authors: Yoon CS, Kang SS Abstract Primary osteosarcomas of the breast are extremely uncommon. Here we describe a case of a 77-year-old woman who presented with a hard mass on her right breast. Mammography and breast ultrasound demonstrated a round-shaped calcified mass on the right breast but the features were not definitely diagnostic. For diagnostic purposes, an excisional biopsy was performed and the mass proved to be a primary osteosarcoma of the breast by pathologic findings. PET-CT and whole body bone scan showed neither evidence of metastasis nor underlying bone lesions. Wide excision without axillary lymph...
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Early-stage cancer detection could reduce breast cancer death rates significantly in the long-term. The most critical point for best prognosis is to identify early-stage cancer cells. Investigators have studied many breast diagnostic approaches, including mammography, magnetic resonance imaging, ultrasound, computerized tomography, positron emission tomography and biopsy. However, these techniques have some limitations such as being expensive, time consuming and not suitable for young women. Developing a high-sensitive and rapid early-stage breast cancer diagnostic method is urgent. In recent years, investigators have paid...
Source: Sensors - Category: Biotechnology Authors: Tags: Review Source Type: research
We describe a patient’s breast density in every mammography report.   Medgadget: Can you explain in simple terms how the ABUS technology works? How does it differ from a conventional mammogram? Dr. Georgia Giakoumis Spear: ABUS is a painless, non-invasive, non-radiation producing technology that uses sound waves (ultrasound) to scan the breast tissue while the patient is lying on her back with her arm raised over her head. The examination is performed by a technologist in about 20 minutes using standardized scanning protocols. The images are then post processed in 3D planes and interpreted by a radiologist. A ma...
Source: Medgadget - Category: Medical Equipment Authors: Tags: Exclusive Oncology Radiology Surgery Source Type: blogs
Abstract: Axillary lymph node (ALN) status is an important prognostic factor for overall breast cancer survival. In current clinical practice, ALN status is evaluated before surgery via multimodal imaging and physical examination. Mammography is typically suboptimal for complete ALN evaluation. Currently, ultrasonography is widely used to evaluate ALN status; nonetheless, results may vary according to operator. Ultrasonography is the primary imaging modality for evaluating ALN status. Other imaging modalities including contrast-enhanced magnetic resonance imaging, computed tomography, and positron emission tomography/compu...
Source: Ultrasound Quarterly - Category: Radiology Tags: Review Article Source Type: research
CONCLUSIONS: In this work, we have defined and demonstrated a methodology to evaluate the productivity of software tools for producing radiology reports in Breast Cancer. We have evaluated that adopting Structured Reporting in mammography and ultrasound studies in breast cancer diagnosis improves the performance in producing reports. PMID: 28220929 [PubMed - as supplied by publisher]
Source: Methods of Information in Medicine - Category: Information Technology Authors: Tags: Methods Inf Med Source Type: research
ConclusionSNB after NACT in case of cN0 is very reliable with high NPV and low FOR. In case of 18F-FDG-PET CT normalization after 6 weeks of chemotherapy and a negative SLN, no ALND has to be performed.Citation Format: Gerber A, Konig L, Millner L, Strotoman L, Khurana A, Kasimir-Bauer S, Moore MW, Cotter PD, Bischoff F. Development of a novel HER2 testing strategy, using image-based cell-sorting to isolate pure cell populations from FFPE upstream of FISH [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res ...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
ConclusionWe believe this preliminary study suggests that tomosynthesis is equivocal to MRI for assessing multifocality in ILC. If confirmed the implications would be a shorter investigative pathway with reduced delays and costs. A larger mutli-centre trial to assess the use of tomosynthesis to replace MRI in patients with ILC is warranted.Citation Format: Ironside A, Hawkesford K, Gomm J, Haywood L, Goulding I, Wang J, Lamaziere A, Poirot M, Silvente-Poirot S, Chelala C, Jones JL. Molecular mediators of mammographic density [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposiu...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
Conclusion:This study has demonstrated that pre-operative MRI leads to additional investigations. Its impact on management is low if the lesion is mammographically occult but visible on ultrasound. In cases with ultrasound occult cancer and those with lobular features on core biopsy, it changes management in a significant proportion and should therefore be considered as a part of the diagnostic work-up.Citation Format: McGarrigle SA, Guinan EM, Hussey J, O'Sullivan J, Boyle T, Hanhauser Y, Al-azawi D, Kennedy MJ, Gallagher DJ, Connolly EM. Unhealthy lifestyle patterns are prevalent in unaffected BRCA mutation carriers 2016...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
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