One ‐year outcomes of bronchial thermoplasty for severe uncontrolled asthma in japan

Source: Respirology - Category: Respiratory Medicine Tags: Bronchoscopy and Interventional Techniques Source Type: research

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We report a 25-year-old woman with persistent dyspnea and wheezes that had been unsuccessfully treated with inhaled beta 2-agonists and steroids for about one year. Spirometry demonstrated a restrictive pattern. Chest CT demonstrated polypoidal lesion in left main bronchus. The lesion was excised via rigid bronchoscopy. Pathology showed a picture of typical bronchial carcinoid. In this patient, due to the lack of awareness, diagnosis of carcinoid was delayed for one year.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Conditions:   Asthma;   Allergic Asthma Intervention:   Procedure: Bronchoscopy Sponsor:   University Medical Center Groningen Recruiting
Source: - Category: Research Source Type: clinical trials
Abstract AIM: The aim of our study was to assess any association between ICS use and tracheobronchomalacia (TBM). METHODS: We conducted a retrospective analysis on asthma and COPD patients with and without TBM. Patients were diagnosed with TBM on the basis of CT scan, flexible bronchoscopy or both. Patients were deemed to be on ICS if they were on treatment for at least 3 months. Simple logistic regression models were used to assess the association between TBM status and each proposed factor. A multivariable logistic regression model was used to assess the association between TBM and steroid dose. RESULT...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Conclusion: This position statement provides practical guidance regarding patient selection and the technical performance of BT for severe asthma.
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
Authors: Matsuo Y, Yamada T, Hiraoka E Abstract Cricoid cartilage fracture is generally caused by significant neck trauma and causes continuous dyspnea, neck pain, or hoarseness developing immediately after the traumatic episode. A 69-year-old woman without any history of trauma was admitted to our hospital with intermittent dyspnea. Six months before admission she had started to complain of dyspnea occurring several times a month without warning, improving spontaneously within a few hours without treatment. Her primary care doctor diagnosed asthma and she was treated with inhaled short-acting beta agonists and glu...
Source: Nagoya Journal of Medical Science - Category: International Medicine & Public Health Tags: Nagoya J Med Sci Source Type: research
Contributor : Guohua ZhenSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiens ; Mus musculus ; Rattus norvegicusBronchial epithelial brushings were obtained by bronchoscopy from 8 steroid-na ïve asthmatics including type 2-low (n=4) and type 2-high asthma (n=4), and 4 healthy controls. The type 2-low and –high asthma was defined by the epithelial expression of a three-gene signature for type 2 status (POSTN, SERPINB2, and CLCA1).
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Mus musculus Rattus norvegicus Source Type: research
Bronchial thermoplasty (BT) is a bronchoscopic procedure for treating severe asthma using thermal energy to reduce airway smooth muscle. There are some reports of complications such as bronchitis and atelectasis due to transient inflammation and oedema, but, to the best of our knowledge, no studies have reported eosinophilic pneumonia (EP) due to BT. Mepolizumab is an anti ‐interleukin‐5 monoclonal antibody that is reportedly effective against eosinophilic inflammation such as bronchial asthma; however, only few studies have reported its use in treating EP. Here, we report the effectiveness of mepolizumab in treating E...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
There are numerous biologics for treating patients with severe asthma. A cost-effective method for selecting the most appropriate biologic therapy for a patient is thus important. Bronchoscopy-guided bronchial...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Case report Source Type: research
Conclusion: Portable CPAP improves exercise capacity in patients with EDAC and may enhance benefits of pulmonary rehabilitation in those patients.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Rehabilitation and chronic care Source Type: research
Conclusions: We observed low % eosinophilia sputum in patients with severe bronchoscopic eosinophilic asthma. Our patients with severe eosinophilic bronchial asthma showed different inflammatory patterns in sputum that could explain different clinical behaviors and therapeutic responses.NeutrophilicEosinophilicMixedPaucigranulocyticpAge (years)263743250.056FEV1%81.780.268.4850.082Eos esput%0.875.20.3
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research
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