Cytokine gene polymorphism (interleukin-1β +3954, Interleukin-6 [−597/−174] and tumor necrosis factor-α −308) in chronic periodontitis with and without type 2 diabetes mellitus

Conclusions: In Malayalam speaking Dravidian population, IL-6 (−597) genotype GA/AA and allele A appears to be protective for CHP with type 2 DM. Allele C of IL-1 β +3954 and allele A of TNF-α −308 appears to be risk factors for CHP individuals.
Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) - Category: Dentistry Authors: Source Type: research