Varian Medical wins Japanese nod for Halcyon oncology radiotherapy system

Varian Medical (NYSE:VAR) said today it won Shonin approval from the Japanese Ministry of Health, Labor and Welfare for its Halcyon image-guided volumetric intensity modulated radiotherapy cancer treatment system. The Palo Alto, Calif.-based company said its Halcyon IMRT system features improvements that make it more comfortable for patients and streamline operator’s workflow, only requiring 9 steps from start to treatment, down from 30 steps in legacy machines. Varian Medical said the device is designed to handle “the majority” of cancer patients, including individuals with prostate, breast, head &neck and other forms of cancer. “Since its introduction just a few months ago, Halcyon has received an enthusiastic response from clinicians around the world and we are pleased that it is now available in Japan. The main goal of the Halcyon development was to increase the availability of cost-effective advanced cancer care worldwide. Achieving Shonin approval is an important milestone in realizing this goal,” oncology systems biz prez Kolleen Kennedy said in a press release. Varian Medical won FDA approval for the Halcyon system in July. The post Varian Medical wins Japanese nod for Halcyon oncology radiotherapy system appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Oncology Regulatory/Compliance Varian Medical Systems Source Type: news

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ConclusionsWe conclude that salivary miR-15a-5p may represent a potential biomarker for individualized treatment decision-making in HNSCC patients.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research
Purpose: Late gastrointestinal (GI) toxicity after radiotherapy for prostate cancer may have significant impact on the cancer survivor's quality of life. To date, little is known about local dose-effects after modern radiotherapy including hypofractionation. In the current study we related the local spatial distribution of radiation dose in the rectum to late patient-reported gastrointestinal (GI) toxicities for conventionally fractionated (CF) and hypofractionated (HF) modern radiotherapy in the randomized HYPRO trial.Material and Methods: Patients treated to 78 Gy in 2 Gy fractions (n = 298) or 64.6 Gy in 3.4 Gy fraction...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
and L Abstract OBJECTIVE: Our study aimed to compare regional node coverage and doses to the organ at risk (OAR) using conventional technique (CT) vs "AMAROS" (AT) vs intensity-modulated radiation therapy (IMRT) techniques in patients receiving regional nodal irradiation (RNI) for breast cancer (BC). METHODS: We included 30 consecutive patients with BC who received RNI including axillary nodes. Two independent and blinded dosimetric RNI plans were generated for all patients. For target volume coverage, we analyzed the V95%, the D95%, the mean and the minimal dose within the nodal station. For hotspo...
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
This article reviews the progress in treatment planning using image-informed tumour biology, from focal dose escalation to the current trend of individualised biological treatment planning using image-derived radiobiological parameters, with the focus on prostate intensity-modulated radiotherapy (IMRT).
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Abstract We propose a multi-view data analysis approach using radiomics and dosiomics (R&D) texture features for predicting acute-phase weight loss (WL) in lung cancer radiotherapy. Baseline weight of 388 patients who underwent intensity modulated radiation therapy (IMRT) was measured between 1 month prior to and 1 week after the start of IMRT. Weight change between 1 week and 2 months after the commencement of IMRT was analyzed, and dichotomized at 5% WL. Each Patient had a planning CT and contours of gross tumor volume (GTV) and esophagus (ESO). A total of 355 features including clinical parameter (CP), GTV and ...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
Objective: To study the dosimetric effect on special reconstruction images obtained from an electrocardiograph-gated four-dimensional computed tomography (ECG 4D-CT) series and compare it with the accumulation dose assessment of ECG 4D-CT.Methods: Fifteen patients underwent ECG 4D-CT scans to obtain a 4D-CT series. The 20 phase images of 0–95% were reconstructed at intervals of 5% of the cardiac cycle by the 4D-CT series. The 4D-CT series was specially reconstructed, and the maximum intensity projection (MIP), minimum intensity projection (MinIP), average intensity projection (AIP), and sum intensity projection (SIP)...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSION: Expert evaluation with qualitative feedback improved contouring compliance. The JCI is not a reliable alternative to expert assessment. Moderate uptake of optional CME content limited evaluation. PMID: 32240907 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
CONCLUSION: Once weekly low dose cisplatin treatment showed lower acute toxicity and a better compliance compared to once every 3 weeks high dose cisplatin treatment at the expense of a lower loco-regional control. PMID: 32212810 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
CONCLUSION: Spatial agreement between methods is relatively good although DVM identified more sub-regions. Reproducibility of identified Ssurf between cohorts is low. PMID: 32224316 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
ConclusionsAdaptive two-step IMRT for NPC demonstrated an excellent 3-year OS with acceptable toxicities. This method may be one treatment option for locally advanced NPC.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
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