The enigma of granulomatous mastitis: A series.
We report our experience with the diagnosis and management of eighteen cases of granulomatous mastitis in the setting of an urban public hospital. The patients were identified after a retrospective review of pathology and surgery databases. Demographic, clinical, radiographic, histopathological data and treatment responses were reviewed. Out of a total of 18 patients, 8 patients were noted to be from Mexico. The mean age at presentation was 35 years and 11 of the 18 patients reported a pregnancy in the last four years. Most cases were unsuccessfully managed as bacterial breast infections initially; definitive treatment involved surgical excision and steroids. A complete symptomatic and radiographic resolution was documented in 8 of the 18 patients. Despite posing a challenge for the unsuspecting physician, an early diagnosis of granulomatous mastitis improves patient outcomes. PMID: 29081405 [PubMed - as supplied by publisher]
Publication date: Available online 7 May 2019Source: The SurgeonAuthor(s): S.P. Russell, C. Neary, S. Abd Elwahab, J. Powell, N. O'Connell, L. Power, S. Tormey, B.A. Merrigan, A.J. LoweryAbstractIntroductionPrimary breast abscesses occur in
Abstract A 15-year-old thoroughbred non-pregnant mare was presented with ongoing inappropriate lactation. The most likely cause, equine Cushing's disease, was ruled out through biochemical testing. Milk cytology and bacterial culture showed no evidence of mastitis or neoplasia. Idiopathic inappropriate lactation was diagnosed and treatment with pergolide was recommended. PMID: 30992600 [PubMed - in process]
CONCLUSIONS: staff training courses are essential to respond to WHO-UNICEF recommendations and to improve the continuity of care for the mother-child dyad. PMID: 30977749 [PubMed - in process]
Conclusions: The fat content and energy value of colostrum did not change according to gestational age or fetal growth.
Conclusion: US can demonstrate or exclude a true mass against the background of a nodular breast parenchyma. Radiologists must be aware of malignant US features to avoid delays in the diagnosis of pregnancy-associated breast cancer.Breast Care
ConclusionAlthough clinical and radiological findings of patients with GM may mimic those of breast carcinoma, our study showed that women of childbearing age, especially among Hispanic ethnicity with a recent history of pregnancy or high prolactin level and newly tender mass-like lesion, in addition to new focal asymmetry on mammogram and heterogeneous hypoechoic irregular-shaped mass on ultrasound exam, should raise concern for GM. Non-invasive approach and clinical follow-up were the preferred treatment method.
CONCLUSION: While the findings must be treated with caution due to small numbers, they suggest benefits for women attending Aboriginal Family Birthing Program services in the urban environment where rates of initiation and continued breastfeeding are lowest. Provision of culturally appropriate support to Aboriginal women during and after pregnancy is key to improving outcomes. PMID: 30104173 [PubMed - as supplied by publisher]
Abstract Sinus-like dilatations of the mammary duct are recognisable in the mammary gland of pregnant and lactating wild European rabbits. These dilatations exhibit a bilaminar epithelial lining, with luminal epithelial cells expressing basal and lateral E-cadherin. Occasional binucleated mammary epithelial cells are present in the luminal layer. Underlying the luminal epithelial cells is a basal layer of cytokeratin 14-positive cells, supported by a thin layer of fibrous tissue. Multi-segmental epithelial proliferation, as indicated by Ki67 expression, is apparent in the luminal epithelial cells, suggesting a cap...
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AbstractThe One Health concept promotes integrated evaluation of human, animal, and environmental health questions to expedite advances benefiting all species. A recognition of the multi-species impact of mastitis as a painful condition with welfare implications leads us to suggest that mastitis is an ideal target for a One Health approach. In this review, we will evaluate the role of the mammary microenvironment in mastitis in humans, ruminants and rabbits, where appropriate also drawing on studies utilising laboratory animal models. We will examine subclinical mastitis, clinical lactational mastitis, and involution-assoc...