ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?

Programmed ribosomal frameshifting (PRF) is a gene expression mechanism which enables the translation of two N-terminally coincident, C-terminally distinct protein products from a single mRNA. Many viruses uti...

Source: Biology Direct - October 16, 2017 Category: Biology Authors: Adam M. Dinan, John F. Atkins and Andrew E. Firth Tags: Research Source Type: research