Evaluation of Cerebrovascular Reactivity in Subjects with and without Obstructive Sleep Apnea

Both obstructive sleep apnea (OSA) and altered cerebrovascular reactivity (CVR) are associated with increased stroke risk. Nevertheless, the incidence of abnormal CVR in patients with OSA is uncertain due to the high variability in the way CVR is measured both within and between studies. We hypothesized that a standardized CVR with a consistent vasoactive stimulus and cerebral blood flow (CBF) measure would be reduced in patients with severe OSA compared with healthy controls.

Source: Journal of Stroke and Cerebrovascular Diseases - September 13, 2017 Category: Neurology Authors: Clodagh M. Ryan, Anne Battisti-Charbonney, Olivia Sobczyk, David J. Mikulis, James Duffin, Joseph A. Fisher, Lashmi Venkatraghavan Source Type: research