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Hodgkin’s lymphoma symptoms: Signs of the cancer you should know

HODGKIN ’S lymphoma is a form of cancer which develops in the lymphatic system - which is part of the immune system.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Authors: Hayashi N, Fujita A, Saikai T, Takabatake H, Sotoshiro M, Sekine K, Kawana A Abstract Anaplastic lymphoma kinase (ALK) rearrangement is most commonly observed in lung adenocarcinoma in a subset of lung cancer. Large-cell neuroendocrine carcinoma (LCNEC) harboring an ALK rearrangement is very rare. Based on the findings from a transbronchial lung biopsy, a 75-year-old non-smoking woman was diagnosed with LCNEC with multiple liver and bone metastases. After seven cycles of cytotoxic chemotherapy, her genotype testing demonstrated ALK rearrangement. Subsequently, she was administered alectinib and exhibited a...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Steven T. Rosen, MD, from the City of Hope, Duarte, CA, discusses the affordability of cancer treatments at the 2017 International Workshop in Non-Hodgkin Lymphoma (iwNHL) in Vancouver, BC, Canada. Th... Author: VJHemOnc Added: 11/21/2017
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
(UNC Lineberger Comprehensive Cancer Center) A grant from The Leukemia&Lymphoma Society will help fund clinical research led by UNC Lineberger's Barbara Savoldo, MD, PhD, into an investigational chimeric antigen receptor (CAR) T-cell treatment for acute lymphoblastic leukemia that would include a built-in 'safety switch.'
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
hiang Epstein-Barr virus (EBV) is closely associated with several lymphomas (endemic Burkitt lymphoma, Hodgkin lymphoma and nasal NK/T-cell lymphoma) and epithelial cancers (nasopharyngeal carcinoma and gastric carcinoma). To maintain its persistence in the host cells, the virus manipulates the ubiquitin-proteasome system to regulate viral lytic reactivation, modify cell cycle checkpoints, prevent apoptosis and evade immune surveillance. In this review, we aim to provide an overview of the mechanisms by which the virus manipulates the ubiquitin-proteasome system in EBV-associated lymphoid and epithelial malignancies, t...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Michael Pfreundschuh, MD from the Saarland University, Homburg, Germany is joined by Ryan Morin, PhD from the BC Cancer Agency, Vancouver, Canada, Reiner Siebert, MD from the Institute of Human Geneti... Author: VJHemOnc Added: 11/20/2017
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
Anas Younes, MD, from the Memorial Sloan Kettering Cancer Center, New York, NY is joined by Eduardo Sotomayor, MD, from the George Washington University School of Medicine & Health Sciences, Washi... Author: VJHemOnc Added: 11/20/2017
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
u Carmen Solcan Our research has focused on in vitro and in vivo evaluations of a new Carmustine (BCNU)-loaded clinoptilolite-based delivery system. Two clinoptilolite ionic forms—hydrogen form (HCLI) and sodium form (NaCLI)—were prepared, allowing a loading degree of about 5–6 mg BCNU/g of zeolite matrix due to the dual porous feature of clinoptilolite. Clinoptilolite-based delivery systems released 35.23% of the load in 12 h for the BCNU@HCLI system and only 10.82% for the BCNU@NaCLI system. The BCNU@HCLI system was chosen to develop gel and cream semisolid dosage forms. The cream (C_BCNU@HCLI) re...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Malignant lymphoma B‐cell type is the most common canine haematopoietic malignancy. Changes in intestinal microbiota have been implicated in few types of cancer in humans. The aim of this prospective and case‐control study was to determine differences in faecal microbiota between healthy control dogs and dogs with multicentric lymphoma. Twelve dogs affected by multicentric, B‐cell, stage III‐IV lymphoma, and 21 healthy dogs were enrolled in the study. For each dog, faecal samples were analysed by Illumina sequencing of 16S rRNA genes and quantitative PCR (qPCR) for selected bacterial groups. Alpha diversity was sig...
Source: Veterinary and Comparative Oncology - Category: Veterinary Research Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusion CT fluoroscopy-guided biopsy of anterior mediastinal masses was safe and had a high diagnostic yield; however, using a thinner biopsy needle significantly increased the risk of a failed diagnosis.
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
This study is registered with ClinicalTrials.gov, number NCT01011920. Findings Between Feb 19, 2010, and Aug 27, 2014, 227 patients were recruited from 53 centres in five countries. 219 of 227 enrolled patients were assessable. Of the 122 patients eligible for the second randomisation, 118 patients were randomly assigned to WBRT or ASCT (59 patients per group) and constitute the study population. WBRT and ASCT were both effective, and achieved the predetermined efficacy threshold of at least 40 progression-free survivors at 2 years among the first 52 patients in both groups D and E. There were no significant differences in...
Source: The Lancet Haematology - Category: Hematology Source Type: research
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