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Clues to MS May Lurk in Gut Bacteria

TUESDAY, Sept. 12, 2017 -- Certain types of bacteria in the gut may play a role in the progression of multiple sclerosis, according to researchers working with mice. The research, the study authors believe, could lead to new ways to treat multiple...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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There are many reasons why a person may feel numbness or tingling in their legs or feet. The most common is sitting in the same position for too long, which reduces blood flow to the legs. Causes for chronic numbness include multiple sclerosis and fibromyalgia. Learn more about symptoms, causes, and treatments here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
ConclusionThe economic costs of MS impose a heavy burden on the patients and their families. Supplementing the information on the cost of MS to society, our finding should be included as background information in decisions on reimbursing and allocating public resources for the well-being of MS patients and their families.
Source: The European Journal of Health Economics - Category: Health Management Source Type: research
Authors: Maurelli M, Bergamaschi R, Antonini A, Fargnoli MC, Puma E, Mallucci G, Totaro R, Girolomoni G Abstract Interferon-beta (IFNβ) are effective treatments for relapsing multiple sclerosis. IFNβ treatment includes subcutaneous (sc) IFNβ-1b, intramuscular and sc IFNβ-1a, and sc pegylated IFNβ-1a (PEG-IFNβ-1a). PEG-IFNβ-1a offers the advantage of a prolonged duration of action with a less frequent administration (every 2 weeks) and a higher patient adherence. However, the use of subcutaneous interferons could be characterized by potential skin toxicity. Injection site reactions...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
First bit of news: I’ve had absolutely no pain in my heel. It’s as good as new. I have to admit I’m still stunned…and I wonder if a more conventional doctor, let’s say a physiotherapist, would have made the connection between my relatively new eyeglass prescription and my heel pain. I doubt it. This makes me wonder how many similar cases there are, of people who think they have plantar fasciitis or tendonitis or, sorry for the mention!  , heel spurs, but whose pain actually originated in a different part of the body, an easy-to-fix part of the body. Mind-blowing, eh? But the reason I&rsq...
Source: Margaret's Corner - Category: Cancer & Oncology Authors: Tags: Blogroll celiac disease curcumin EBV Epstein-Barr virus inflammatory bowel disease lupus multiple sclerosis rheumatoid arthritis type 1 diabetes Source Type: blogs
Contributor : Yun LiuSeries Type : Methylation profiling by arrayOrganism : Homo sapiensGenome-wide DNA methylation level was studied to determine whether multiple sclerosis patients (cases) has methylation differences comparing to normal controls in PBLs.We used Illumina HumanMethylation450 BeadChip array to determine the genome-wide DNA methylation difference in peripheral blood from multiple sclerosis patients (cases) and normal controls
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research
Nicole Ziliotto, Marcello Baroni, Sofia Straudi, Fabio Manfredini, Rosella Mari, Erica Menegatti, Rebecca Voltan, Paola Secchiero, Paolo Zamboni, Nino Basaglia, Giovanna Marchetti, Francesco Bernardi
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractPurpose of reviewVolumetric analysis of brain imaging has emerged as a standard approach used in clinical research, e.g., in the field of multiple sclerosis (MS), but its application in individual disease course monitoring is still hampered by biological and technical limitations. This review summarizes novel developments in volumetric imaging on the road towards clinical application to eventually monitor treatment response in patients with MS.Recent findingsIn addition to the assessment of whole-brain volume changes, recent work was focused on the volumetry of specific compartments and substructures of the central...
Source: Current Treatment Options in Neurology - Category: Neurology Source Type: research
Conclusion These findings not only add to the body of knowledge in health science, but also serve as an important motivation for further theory development and research in this context. Nurses and health professions can also benefit from a deeper understanding of coping concept in providing and planning healthcare for these patients.
Source: International Journal of Nursing Sciences - Category: Nursing Source Type: research
Condition:   Multiple Sclerosis Interventions:   Other: Pilates exercises;   Other: Home exercise program Sponsors:   Dokuz Eylul University;   Izmir Katip Celebi University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies to desmoglein 3 (Dsg3). Several autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and myasthenia gravis, have defective central and/or peripheral B cell tolerance checkpoints, leading to an accumulation of polyreactive B cells that is thought to provide the first hit toward the development of autoimmunity. We investigated whether PV patients have intact tolerance checkpoints to self-antigens other than Dsg3, which would differentiate the mechanism of autoimmunity in PV from those of other autoimmune diseases.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Adaptive and Auto-Immunity Source Type: research
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