Diversity of TP53 Mutations in CLL: Retrospective Analysis of 450 Mutations from the French Innovative Leukemia Organization (FILO) Group

In CLL, TP53 mutations are associated with adverse prognosis and chemotherapy resistance. Little is known on the functional effect of the various alterations and of their associations.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Myriam Hormi, Fanny Baran-Marszak, Lauren V éronèse, Pierre Sujobert, Frederic Davi, Stéphanie Poulain, Marie-Hélène Estienne, Audrey Bidet, Eric Delabesse, Stéphane Giraudier, Cédric Pastoret, Pascale Cornillet-Lefebvre, Sophy Laibe, Laurence Lode Source Type: research