Association of Complex Karyotype with Inferior Survival in Mantle Cell Lymphoma is Independent of Specific Cytogenetic Abnormalities

Risk stratification of newly diagnosed patients with mantle cell lymphoma (MCL) is primarily based on the MCL international prognostic index (MIPI) and Ki67. Single-center studies have reported inferior outcomes in patients with a complex karyotype (CK), but this remains an area of controversy.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: I. Brian Greenwell, Ashley D. Staton, Michael Lee, Jeffrey M. Switchenko, Joseph Maly, Kristie Blum, Natalie Grover, Stephanie Mathews, Steven Park, Max Gordon, Alexy Danilov, Timothy Fenske, Narendranath Epperla, Mehdi Hamadani, Christopher Flowers, Jona Source Type: research