A hybrid parameter estimation algorithm for beta mixtures and applications to methylation state classification.

CONCLUSIONS: The hybrid algorithm between likelihood-based component un-mixing and moment-based parameter estimation is a robust and efficient method for beta mixture estimation. We provide an implementation of the method ("betamix") as open source software under the MIT license. PMID: 28828033 [PubMed]
Source: Algorithms for Molecular Biology : AMB - Category: Molecular Biology Authors: Tags: Algorithms Mol Biol Source Type: research