Porphyromonas Gingivalis and IgG1 and IgG2 Subclass Antibodies in Patients with Juvenile Idiopathic Arthritis
AbstractPurpose of ReviewTo determine the efficacy of mindfulness-based interventions (MBIs) on clinical and patient-reported outcomes in rheumatoid arthritis (RA).Recent FindingsWe identified randomized clinical trials from inception through April 2018 from MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, the Cochrane Library, and hand searches. After screening 338 references, we included five trials with one post-hoc analysis that evaluated MBIs and collectively included 399 participants. Outcome instruments were heterogeneous across studies. Three studies evaluated RA clinical outcomes by a rheumatologist; one study f...
ConclusionMultidisciplinary management of septic arthritis improved treatment success.Level of evidenceIII, Retrospective comparative study.
(MedPage Today) -- Risk is highest in the first year after juvenile arthritis diagnosis
CONCLUSION: RAPID-3 improvement of 3.8/30 units appears clinically meaningful. PMID: 30323010 [PubMed - as supplied by publisher]
CONCLUSION: We identified potential elemental ultrasonographic abnormalities and entheseal sites that could distinguish PsA and controls. This information will contribute to the development of a new sonographic score for assessment of enthesitis in patients with PsA. PMID: 30323008 [PubMed - as supplied by publisher]
CONCLUSION: VLDA and MDA definitions are more stringent than DAPSA and cDAPSA definitions for the assessment of PsA. The relevance of residual disease to patients, however, remains to be determined. [Clinical Trial registration: ClinicalTrials.gov NCT00245960]. PMID: 30323006 [PubMed - as supplied by publisher]
Authors: Ruwaard J, van der Vlugt ER, Wolbink G Abstract Biological treatment is an effective treatment for various chronic inflammatory diseases1,2 Nevertheless, reports of paradoxical immune-mediated inflammation induced by biologicals are increasing3. PMID: 30323005 [PubMed - as supplied by publisher]
We describe the neurodevelopmental needs in this young cohort at study enrollment as reported by the parent or primary care-giver. We present data that supports that young boys with DMD have a high prevalence of neurodevelopmental needs as reported by parent or care-giver. Further, boys with DMD mutations between exons 45-50 reported higher cognitive problems. There was no relationship between neurodevelopmental needs and glucocorticoid use. We conclude that there is an unmet, critical medical need in DMD to develop pragmatic solutions for early detection and intervention of neurodevelopmental needs during a window of neu...
In the seven years since the original Wheat Belly book hit bookstores and turned the nutritional world topsy-turvy and millions of people have engaged in a grain-free lifestyle, many unique lessons have been learned. Even though I had engaged the practices of this lifestyle for a number of years and in thousands of people before I broadcast these ideas through books, expanding the audience to many more people yielded feedback on an enormous scale, new lessons that even surprised me. Among the new lessons learned along the way: Plantar fasciitis—I did not expect to have so many people report that this painful conditi...
Conclusions: Our results cumulatively suggest that periodontoid calcification is an aging-related reaction and that calcification per se does not always cause neck pain. Periodontoid calcification was observed more frequently in patients with pseudogout of the peripheral joints and in those with acute neck pain than in asymptomatic control patients. PMID: 30322243 [PubMed - as supplied by publisher]