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A higher volume of fibrotic tissue on virtual histology prior to coronary stent implantation predisposes to more pronounced neointima proliferation.

CONCLUSION: Lesions with more voluminous fibrotic tissue pre-PCI show more pronounced in-stent neointima proliferation, even after correction for lesion plaque volume. PMID: 28799447 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research

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Abstract Contrast-induced nephropathy (CIN) is a serious complication in patients undergoing percutaneous coronary intervention (PCI), and is associated with higher morbidity and mortality. The limiting volume of contrast medium is safest and most reliable strategy for CIN prevention. Intravascular ultrasound (IVUS) serves as an attractive alternative imaging tool to angiography in many steps during PCI, thereby reducing the use of contrast agents. Here, we reported a case of successfully treated unprotected left main bifurcation lesion with heavily calcified and diffuse lesion under the IVUS-guided PCI using low ...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
Conclusions -In the present trial which allowed broad inclusion criteria, the novel RES met the prespecified criteria for noninferiority compared with ZES for the primary endpoint of target lesion failure at 12 months, and had similar measures of late lumen loss. These findings support the safety and efficacy of RES in patients representative of clinical practice. Clinical Trial Registration -URL: www.ClinicalTrials.gov Unique Identifier: NCT01995487. PMID: 28794001 [PubMed - as supplied by publisher]
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
Aim: The use of intravascular ultrasound (IVUS) or Optical coherence tomography (OCT) to guide stent placement in percutaneous coronary intervention (PCI) leads to better clinical outcomes than use of angiography guidance. We hypothesis which image-assisted PCI could lead better clinical outcomes in acute myocardial infarction (MI) patients.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Publication date: Available online 27 July 2017 Source:Journal of Cardiology Cases Author(s): Fumiya Anzai, Hiroyuki Kunii, Yuki Kanno, Masashi Kamioka, Atsushi Kobayashi, Hitoshi Suzuki, Shuichi Saitoh, Yasuchika Takeishi Pseudoxanthoma elasticum (PXE) is caused by loss-of-function mutations of the ATP-binding cassette subfamily C member 6 gene. A 58-year-old man was diagnosed as having PXE based on typical findings in orbital and skin biopsies. Coronary computed tomography (CT) showed severe coronary stenosis in the proximal right coronary artery (RCA), and chronic total occlusion (CTO) of the mid left anterior descendi...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
AbstractOptical coherence tomography (OCT) is an intra-coronary diagnostic technique that provides detailed imagings of blood vessels in the current cardiac catheterization laboratory. The higher resolution of OCT often provides superior delineation of each structure compared with intravascular ultrasound (IVUS), and it can reliably visualize the microstructure of normal and diseased arteries. The capabilities of OCT are well suited for the identification of calcified plaque and neointima formation after stent implantation. It has been reported that OCT-guided percutaneous coronary intervention (PCI) resulted in equivalent...
Source: Cardiovascular Intervention and Therapeutics - Category: Cardiology Source Type: research
Authors: Koide M, Kato M, Usui K, Mera K, Tsubakimoto Y, Isodono K, Sakatani T, Matsuo A, Inoue K, Fujita H Abstract The most important factor for preventing contrast-induced nephropathy (CIN) during percutaneous coronary intervention (PCI) in patients with severe renal dysfunction is to minimize the contrast volume. Herein, we report a successful case of complete revascularization after 3 separate PCI procedures using a super-low volume of contrast medium in a patient with 3-vessel disease, including two chronic total occlusions (CTOs). A 70-year-old man having exertional angina despite maximal medical therapy was...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
Revascularization of significant Left Main Stem (LMS) disease improves clinical outcomes. This can be achieved through either Coronary Artery Bypass Grafting or Percutaneous coronary intervention. Defining a significant stenosis of the LMS can be challenging and debatable, as most data have been derived using angiographic assessment alone, with a threshold of 50% luminal stenosis used as a marker of functional significance. The use of adjunctive technologies like Intravascular Ultrasound and Fractional Flow Reserve has improved our ability to accurately assess the anatomical severity and physiological significance of coron...
Source: Cardiovascular Revascularization Medicine - Category: Cardiology Authors: Source Type: research
Publication date: Available online 9 June 2017 Source:Journal of Cardiology Cases Author(s): Tomo Komaki, Shin-ichiro Miura, Kouki Gondo, Ayumi Nakamura, Amane Ike, Akira Matsunaga, Keijiro Saku A 31-year-old female with an 18-year history of systemic lupus erythematosus (SLE) complained of epigastralgia and consulted the emergency outpatient department at our hospital. Her physical examination revealed tenderness at the scrobiculus cordis, which was a non-specific symptom of coronary heart disease (CHD). We ultimately gave a diagnosis of acute myocardial infarction based on coronary angiography and performed percutaneous...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Conclusions IVUS-detected subintimal tracking is observed in approximately one-half of all successful CTO PCI cases and is associated with an expected higher, yet acceptable, event rate with no difference in minimal stent area or edge dissection among patients undergoing contemporary hybrid CTO PCI.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - Category: Cardiology Authors: Tags: Coronary Source Type: research
Detection of obstructive disease of the left main coronary artery (LMCA) is relatively unusual in the catheterisation laboratory, as it accounts for approximately 4 % of all coronary angiograms, with isolated LMCA disease observed in only 5 –10 % of these cases.1
Source: Radcliffe Cardiology - Category: Cardiology Authors: Source Type: research
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