Delirium Following Topical Application of Compounded Creams Containing Multiple Analgesic Medications in Geriatric Patients: Two New Cases
Compounded topical formulations containing multiple classes of analgesic medications are becoming increasingly common; however, the current literature is sparse regarding complications such as delirium and inadvertent overdose in the elderly.
A regulatory framework is in place for additional Rx-to-OTC switches where appropriate, including the opioid overdose antidote naloxone. It is up to sponsors to work with the FDA to deliver more switched products.
It has been 5 years since the last update on infections in solid organ transplant (SOT) recipients was published in Infectious Diseases Clinics of North America in 2013. There has been a 20% increase in the number of organ transplants over the last 5 years,1 largely driven by increase in the number of deceased donors, with more than 33,000 transplants performed annually in the United States. Our nation is facing an unprecedented opioid epidemic, which is currently accounting in several parts of the country for a quarter of organ donors who die of overdose.
Buprenorphine is an effective medication for the treatment of opioid addiction, but current barriers to buprenorphine access limit treatment availability for many patients. We identify and characterize regions within the United States (US) with poor buprenorphine access relative to the observed burden of overdose deaths.
Opioid use has reached epidemic proportions over the past decade, becoming one of America’s highest-priority public health issues. With opioid abuse spiraling out of control, lawmakers, regulators, and health professionals are scrambling to better understand key drivers of this issue and develop an effective action plan. Although the devastating impact of opioids on families and communities is well known, less focus has been given to how it affects the workplace and the role that employers and health care plan sponsors can play in combating it. Opioids’ impact on America’s workforce Opioid use is surging ...
(MedPage Today) -- Many patients may be receiving excess dose for their weight
Similar to many states around the country, New Jersey continues to experience a growing opioid epidemic.Among many professionals battling this epidemic on the frontline are New Jersey’s 32,000 EMS providers. Compounding the problem with illicit opioid use is the high incidence of fentanyl-related overdoses within the state. The opioid epidemic is so severe that, according to New Jersey's real-time dashboard of opioid-related data, it has already claimed 1,562 lives in the state from January 1 through July 7, placing us on track to exceed previous annual state opioid overdose death statistics. New Jersey’s EMS B...
As a physician licensed to prescribe narcotics, I am legally permitted to prescribe the powerful opioid methadone (also known by the brand name Dolophine ) to my patients suffering from severe, intractable pain that hasn ’t been adequately controlled by other, less powerful pain killers. Most patients I encounter who might fall into that category are likely to be terminal cancer patients. I’ve often wondered why I am approved to prescribe methadone to my patients as a treatment for pain, but I am not allowed to prescribe methadone to taper my patients off of a physical dependence the...
The Florida spine surgeon was convicted by a federal jury on charges related to making counterfeit oxycodone in his office, which was linked to the overdose death of a 34-year-old woman.Medscape Medical News
Attorney General Jeff Sessions put in a plug for President Donald Trump's Supreme Court nominee on Friday as he touted the role of law enforcement in reducing addiction and overdose deaths plaguing Maine and New England.
The Gosport Independent Panel into patient deaths from opiate overdose concluded that: Opiates were used without appropriate indication; Opiates were started at inappropriately high doses Opiates were combined with other drugs in high doses.