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Delirium Following Topical Application of Compounded Creams Containing Multiple Analgesic Medications in Geriatric Patients: Two New Cases

Compounded topical formulations containing multiple classes of analgesic medications are becoming increasingly common; however, the current literature is sparse regarding complications such as delirium and inadvertent overdose in the elderly.
Source: Psychosomatics - Category: Psychiatry & Psychology Authors: Source Type: research

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BACKGROUND: Drug overdose mortality is a major public health concern in the United States, with prescription opioids contributing substantially to recent increases in drug overdose deaths. Compared to unintentional drug overdose deaths, relatively little d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Opioid overdose deaths have fallen 6.5 percent in Colorado in the last two years, since stores there were able to start legally selling recreational marijuana, according to a new study.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
AbstractPurpose of ReviewAcetaminophen (paracetamol, APAP) is the most commonly prescribed analgesic for the treatment of acute pain. It is also the most commonly prescribed analgesic and antipyretic for children. There has been extensive clinical use of acetaminophen in nonparenteral forms (e.g., oral or rectal) for over six decades and over 20  years of clinical experience outside the USA with the intravenous (IV) use of acetaminophen.Recent FindingsIn the USA, IV acetaminophen was approved by the Food and Drug Administration in November 2010. Studies indicate that IV acetaminophen is as effective for acute pain rel...
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
A coalition of 41 states' attorneys general have served five major opioid manufacturers with subpoenas seeking information about how these companies marketed and sold prescription opioids. The coalition is also demanding documents and information related to distribution practices from three drug distributors. The investigative subpoenas and document requests were sent to pharmaceutical manufacturers Endo International, Janssen Pharmaceuticals, Teva Pharmaceutical Industries Ltd./Cephalon Inc. and Allergan. The group also served a supplemental investigative subpoena to Purdue Pharma. Documents were also requested of three ...
Source: Policy and Medicine - Category: American Health Authors: Source Type: blogs
Abstract This educational review presents an overview of opioid use disorder, misuse and overdose among adolescents, and the clinical implications for anesthesiologists. It provides definitions, discusses the epidemiology worldwide, (focusing on North America), and emphasizes the clinical implications of patients with chronic opioid exposure, including perioperative pain management, as well as opioid overdose and prolonged use of opioids after acute exposure. In the USA, opioid use disorder and negative outcomes related to opioids rose dramatically from 1999-2010; concomitantly heroin use and fatal overdoses have ...
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Tags: Paediatr Anaesth Source Type: research
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Source: the Mail online | Health - Category: Consumer Health News Source Type: news
On September 14, 2017, 27-year old Taquisha Desirae McKitty was brought to Brampton Civic Hospital suffering from a drug overdose. After six days, doctors declared her brain dead despite her family’s wishes. The family filed an injunction to keep McKitty on organ support. On September 28th, Superior Court Justice M.J. Shaw extended that injunction to October 17th so that the family could obtain a second opinion from another physician. It is unclear that they have obtained such an opinion.
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: Health Care syndicated Source Type: blogs
Despite the focus on appropriate use of opioids for pain management, many hospitals continue to see adverse events in which patients are injured from unintentional overdoses. To help hospitals prevent patient harm from the use of opioids, ECRI Institute Patient Safety Organization (PSO) conducted a deep dive analysis of adverse events related to opioids in the acute care setting. Executive brief, a leadership infographic, and an interactive tool are available for free download by registering with ECRI.
Source: HSR Information Central - Category: International Medicine & Public Health Source Type: news
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Source: News stories via the Rural Assistance Center - Category: Rural Health Source Type: news
We examined predictors of reported naloxone administration in the past year.
Source: Journal of Substance Abuse Treatment - Category: Addiction Authors: Source Type: research
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