Submit Application early(?)

Ok I have been scanning the ptcas 5million page pdf and wanted to ask *just in case* if it is ok to submit the ptcas application before the letters of recommendation, transcripts etc are received. I've been holding off because there is a problem in the system where it will not allow you to enter same email for a LOR if you have used that email already to request verification of hours. I got feedback that this is a known issue and they're working to fix it. Meanwhile I'm sitting here with... Submit Application early(?)
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Source Type: forums