Glaukos touts iStent study with topical travoprost

Glaukos (NYSE:GKOS) touted data today from a 53-patient glaucoma study showing that its iStent device combined with topical travoprost reduced mean intraocular pressure by 35% after 18 months of follow-up. The company’s flagship device is designed to lessen IOP by restoring the natural outflow of aqueous humor through the conventional pathway in a patient’s eye. Get the full story at our sister site, Drug Delivery Business News. The post Glaukos touts iStent study with topical travoprost appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Clinical Trials Drug-Device Combinations Optical/Ophthalmic Pharmaceuticals Stents Wall Street Beat Glaukos Source Type: news

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New J. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9NJ05967A, PaperMaja Zivkovic, Marko Zlatanovic, Nevena Zlatanovic, Jasmina Djordjevic Jocic, Mladjan Golubovi ć, Aleksandar M Veselinović Actin-binding kinases are enzymes involved in the regulation of actin polymerization and microtubule disassembly. The inhibition of actin-binding kinases can be used in the treatment of glaucoma, since it relaxes... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
AbstractGlaucoma, a multifactorial neurodegenerative disease characterized by progressive loss of retinal ganglion cells and their axons in the optic nerve, is a leading cause of irreversible vision loss. Intraocular pressure (IOP) is a risk factor for axonal damage, which initially occurs at the optic nerve head (ONH). Complex cellular and molecular mechanisms involved in the pathogenesis of glaucomatous optic neuropathy remain unclear. Here we define early molecular events in the ONH in an inherited large animal glaucoma model in which ONH structure resembles that of humans. Gene expression profiling of ONH tissues from ...
Source: Molecular Neurobiology - Category: Neurology Source Type: research
Conditions:   Primary Open Angle Glaucoma;   Drug Effect Interventions:   Drug: Ginkgo biloba capsule;   Drug: Placebos Sponsor:   Zhongshan Ophthalmic Center, Sun Yat-sen University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Eye Diseases;   Ophthalmic Trauma;   Mitochondrial DNA;   Age Related Macular Degeneration;   Glaucoma;   Diabetic Retinopathy Intervention:   Other: Sample collection from tissue discard Sponsor:   The University of Texas Medical Branch, Galveston Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma;   Cataract Interventions:   Procedure: phacoemulsification and Intraocular lens implantation;   Diagnostic Test: Ultrasound Biomicrosopy (UBM) Sponsor:   Mai Nasser Abd Elmohsen Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Eye Diseases;   Ophthalmic Trauma;   Mitochondrial DNA;   Age Related Macular Degeneration;   Glaucoma;   Diabetic Retinopathy Intervention:   Other: Sample collection from tissue discard Sponsor:   The University of Texas Medical Branch, Galveston Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma;   Cataract Interventions:   Procedure: phacoemulsification and Intraocular lens implantation;   Diagnostic Test: Ultrasound Biomicrosopy (UBM) Sponsor:   Mai Nasser Abd Elmohsen Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma;   Ocular Hypertension;   Filtering Surgery Interventions:   Procedure: phacotrabeculectomy;   Procedure: ExPress antiglaucoma surgery combined with phacoemulsification Sponsor:   Medical University of Bialystok Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study included 273 patients (160 men and 113 women, ave...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Conclusions: While the ophthalmic community has traditionally viewed glaucoma as the classic ocular anomaly of CMTC, this dataset advocates for the prompt investigation of posterior segment abnormalities as well. However, our understanding of CMTC's ocular anomalies is complicated by a lack of reporting and/or incomplete (or nonexistent) ophthalmic examinations, and we strongly encourage comprehensive ophthalmic examinations for all CMTC patients at the time of diagnosis, followed by appropriate screening and surveillance throughout life. We believe these recommendations will spur additional data and disease insights that ...
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
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