Boehringer and Lilly to assess empagliflozin for chronic kidney disease

Boehringer Ingelheim, in collaboration with Eli Lilly and Company, is set to evaluate empagliflozin in a new clinical outcomes trial to treat patients suffering from chronic kidney disease.
Source: Drug Development Technology - Category: Pharmaceuticals Source Type: news

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Publication date: Available online 24 April 2019Source: Gynecologic Oncology ReportsAuthor(s): Brooke Liang, Sara S. Lange, L. Stewart Massad, Rebecca Dick, Kathryn A. Mills, Andrea R. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Katherine C. Fuh, David G. Mutch, Matthew A. Powell, Lindsay M. KurokiAbstractObjectiveTo assess the renal outcomes of gynecologic oncology patients who present with hydronephrosis and acute kidney injury (AKI), have
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
(Natural News) Researchers came up with a list of drinks that could harm the kidneys if consumed in excessive quantities. They identified beer, sugary drinks, and two healthy types of beverages – fruit juices and tea – as potential causes of chronic kidney disease. The most egregious offenders were carbonated and sweetened fruit drinks. Guzzling these bubbly, sweet beverages on...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Sara AlMarabeh, Mohammed H. Abdulla and Ken D. O'Halloran* Department of Physiology, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland Renal sensory nerves are important in the regulation of body fluid and electrolyte homeostasis, and blood pressure. Activation of renal mechanoreceptor afferents triggers a negative feedback reno-renal reflex that leads to the inhibition of sympathetic nervous outflow. Conversely, activation of renal chemoreceptor afferents elicits reflex sympathoexcitation. Dysregulation of reno-renal reflexes by suppression of the inhibitory refle...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conditions:   Renal Insufficiency, Chronic;   Kidney Failure, Chronic;   Exercise Intervention:   Sponsors:   Skane University Hospital;   Cardenal Herrera University;   Aristotle University Of Thessaloniki;   Queen Margaret University;   Universiteit Antwerpen;   Tartu University Hospital;   University of Pisa;   King's College London;   Sozialstiftung Bamberg;   Azienda Ospe daliera Bianchi-Melacrino-Morelli Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Renal Insufficiency, Chronic Interventions:   Drug: Chlorthalidone;   Drug: Bumetanide Sponsor:   Hospital General de México Dr. Eduardo Liceaga Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Renal Insufficiency, Chronic;   Kidney Failure, Chronic;   Exercise Intervention:   Sponsors:   Skane University Hospital;   Cardenal Herrera University;   Aristotle University Of Thessaloniki;   Queen Margaret University;   Universiteit Antwerpen;   Tartu University Hospital;   University of Pisa;   King's College London;   Sozialstiftung Bamberg;   Azienda Ospe daliera Bianchi-Melacrino-Morelli Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Renal Insufficiency, Chronic Interventions:   Drug: Chlorthalidone;   Drug: Bumetanide Sponsor:   Hospital General de México Dr. Eduardo Liceaga Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Acute kidney injury (AKI) is a common complication after allogeneic stem cell transplantation (ASCT); however, its incidence and outcome in patients transplanted for multiple myeloma (MM) is unknown. Our results suggest that AKI occurs with low incidence and reduced severity after ASCT for MM. Prophylactic measures in patients with preexisting –kidney failure may further reduce this risk. AbstractAcute kidney injury (AKI) is a common complication after allogeneic stem cell transplantation; however, its incidence and outcome in patients transplanted for multiple myeloma (MM) is unknown. We evaluated the incidence, sev...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This study sought to determine whether lower extremity vascular dysfunction, as assessed by passive leg movement (PLM), is impaired in patients with chronic kidney diseae (CKD). As hypothesized, we observed a significantly diminished hyperemic response during PLM in CKD patients, suggesting impaired blood flow regulation and vascular dysfunction within the lower ‐limb vasculature. We identified significant relationships between the hyperemic responses during PLM and kidney function, potentially providing insight on the dynamic relationship between kidney health, endothelial function, and risk of CVD development in older ...
Source: Physiological Reports - Category: Physiology Authors: Tags: Original Research Source Type: research
Najmi Diabetes and hypertension are the two major causes of chronic kidney disease (CKD). Epidemiological studies have found poor knowledge about the CKD among the general population. Hence, this study aimed to assess the awareness of CKD among type 2 diabetes mellitus (T2DM) patients in India. Patients with confirmed T2DM were included in the study. Patients receiving dialysis or with a history of a kidney transplant were excluded. A validated questionnaire was used to assess knowledge about CKD. Demographic characteristics were presented using descriptive statistics and trends in groups were calculated using the chi-...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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