Flagellin concentrations in expectorations from cystic fibrosis patients

Conclusions: This is the first demonstration that flagellin is present in the sputum of patients. Thus, attempts to down regulate inflammation by the use of TLR5 (flagellin receptor) antagonists remain a possibility. However, this result needs to be extended to a larger number of patients to validate it for future research on this subject.
Source: BMC Pulmonary Medicine - Latest articles - Category: Respiratory Medicine Authors: Source Type: research