Post-acute delivery of GABAA receptor alpha5-antagonist S44819 promotes motor-coordination recovery, prevents secondary brain atrophy and reduces astrocytic scar formation after transient middle cerebral artery occlusion in mice (P3.109)

Conclusions:Our data provide strong evidence that S44819 enhances neurological recovery in the post-acute stroke phase.Disclosure: Dr. Wang has nothing to disclose. Dr. Sanchez-Mendoza has nothing to disclose. Dr. de Carvalho has nothing to disclose. Dr. Kaltwasser has nothing to disclose. Dr. Machado has received personal compensation as an employee of Servier (France), Dr. Doeppner has nothing to disclose. Dr. Bassetti has received personal compensation for activities with Servier as an Advisory Board Member. Dr. Bassetti has received research support from Servier. Dr. Hermann has received personal compensation for activities with Servier as Advisory board. Dr. Hermann has received research support from Servier.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Wang, Y.-c., Sanchez-Mendoza, E., de Carvalho, T. S., Kaltwasser, B., Machado, P., Doeppner, T. R., Bassetti, C. L., Hermann, D. M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research