Apremilast for the treatment of psoriatic arthritis.

Apremilast for the treatment of psoriatic arthritis.
Dermatol Online J. 2017 Feb 15;23(2):
Authors: Martin BC, Thomas LW, Dann FJ
Abstract
Psoriatic arthritis (PsA) is a chronic inflammatoryarthropathy that affects joints and entheses andis associated with psoriasis (PsO). There are fiveclinical patterns of PsA: symmetrical polyarthritis,distal interphalangeal arthropathy, asymmetricaloligoarthritis, arthritis mutilans, and spondylitis, withor without sacroiliitis. Concerning PsA, the goals oftherapy are to control inflammation, prevent articulardamage, and reduce discomfort in the affected joints.Although there are many therapeutic options forthe treatment of PsAs, physicians most often beginwith nonsteroidal anti-inflammatory drugs (NSAIDs)for mild disease. Disease-modifying anti-rheumaticdrugs (DMARDS) are reserved for moderate to severedisease. Apremilast may be a useful option for somepatients.
PMID: 28329487 [PubMed - in process]

Source: Dermatol Online J - February 15, 2017 Category: Dermatology Authors: Martin BC, Thomas LW, Dann FJ Tags: Dermatol Online J Source Type: research