Two new secolignans with in vitro anti-inflammatory activities from Urtica fissa rhizomes

AbstractTwo new secolignans, urticin A (1) and urticin B (2), were isolated from the ethanol extract ofUrtica fissa rhizomes. Their structures were elucidated on the basis of extensive spectroscopic evidence (UV, IR, HR-ESI –MS, and NMR). Urticin A and urticin B possessed in vitro anti-inflammatory activities, which significantly inhibited the TNF-α and NO release induced by LPS in RAW 264.7 cells.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research