Early promise, and caution, in measles virus cancer therapy

NEW YORK (Reuters Health) - Mayo Clinic researchers stirred excitement on Thursday by saying they had treated a patient's blood cancer with a specially engineered measles virus, but even scientists involved in the work caution the response does not prove they have a cure.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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What’s the other side of the “I can never die?” plaint of the autism parent? I’ve done a lot of writing about the need for more protections of our vulnerable guys who do not live with us. Even so, for many of us that is not a sustainable solution. And we are not the center of the issue, even though we love our children and want to protect them. No, they themselves are. And it is their right as human beings to claim their independence if that is what they wish. So — perhaps we parents can take a lesson from — of all things — the story of Abraham and Isaac. Not the sacrifice part &md...
Source: Susan's Blog - Category: Child Development Authors: Tags: Uncategorized Source Type: blogs
A young boy in Pakistan receives an oral polio vaccine (OPV). Over the last 30 years huge progress has been made against polio and it is now only endemic in 2 countries, Afghanistan and Pakistan, with only 33 cases confirmed cases last year. Credit: Ashfaq Yusufzai/IPSBy Tharanga YakupitiyageUNITED NATIONS, May 1 2019 (IPS) Since the introduction of vaccines, diseases such as measles and polio were quickly becoming a thing of the past. However, the world’s progress on immunisation is now being threatened. According to the World Health Organisation (WHO), 85 percent of the world’s children received basic va...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Featured Global Headlines Health IPS UN: Inside the Glasshouse North America Population Regional Categories TerraViva United Nations diptheria-tetanus-pertussis (DTP) human papillomavirus (HPV) Measles Vaccines World Health Organ Source Type: news
Mark K. Slifka1* and Ian J. Amanna2 1Division of Neuroscience, Oregon National Primate Research Center, Oregon Health &Science University, Beaverton, OR, United States2Najít Technologies, Inc., Beaverton, OR, United States Vaccines play a vital role in protecting our communities against infectious disease. Unfortunately, some vaccines provide only partial protection or in some cases vaccine-mediated immunity may wane rapidly, resulting in either increased susceptibility to that disease or a requirement for more booster vaccinations in order to maintain immunity above a protective level. The durability of a...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Alla S. Koltsova1,2, Anna A. Pendina1, Olga A. Efimova1*, Olga G. Chiryaeva1, Tatyana V. Kuznetzova1 and Vladislav S. Baranov1,2 1D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia 2Department of Genetics and Biotechnology, Saint Petersburg State University, Saint Petersburg, Russia In the present review, we focus on the phenomenon of chromothripsis, a new type of complex chromosomal rearrangements. We discuss the challenges of chromothripsis detection and its distinction from other chromoanagenesis events. Along with already known causes and mechanisms, we introdu...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Unvaccinated individuals have been the focus of attention during this year’s measles outbreaks. A record 704 cases of the illness have been confirmed in 22 states so far in 2019, and the CDC says the majority of those diagnoses have been in unvaccinated people. Health officials have repeatedly warned nearly everyone to get the shot if they haven’t already — sometimes threatening fines for those who refuse. “Over 90% of the measles cases that have occurred in the U.S. have occurred in unvaccinated persons,” says Dr. William Schaffner, a professor of preventive medicine and infectious diseases a...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized public health Source Type: news
Poshmaal Dhar1 and Julie McAuley2* 1Faculty of Health, School of Medicine, Deakin University, Geelong, VIC, Australia 2Department of Microbiology and Immunology, Peter Doherty Institute, University of Melbourne, Melbourne, VIC, Australia The family of cell surface (cs-) mucins are constitutively expressed at the cell surface by nearly all epithelial cells, beneath the gel-mucin layer. All cs-mucin family members have structural features that enable them to act as a releasable decoy barrier to mucosal pathogens, by providing ligands for pathogen binding and the ability to shed the bound extracellular domain. Due ...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
María Maximina B. Moreno-Altamirano1*, Simon E. Kolstoe2 and Francisco Javier Sánchez-García1* 1Laboratorio de Inmunorregulación, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico 2School of Health Sciences, University of Portsmouth, Portsmouth, United Kingdom Over the last decade, there has been significant advances in the understanding of the cross-talk between metabolism and immune responses. It is now evident that immune cell effector function strongly depends on the metabolic pathway in w...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Eun-Ju Ko, Sabrina Helmold Hait, Gospel Enyindah-Asonye, Mohammad Arif Rahman, Tanya Hoang and Marjorie Robert-Guroff* Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States Inducing strong mucosal immune responses by vaccination is important for providing protection against simian immunodeficiency virus (SIV). A replicating adenovirus type 5 host range mutant vector (Ad5hr) expressing SIV proteins induced mucosal immune responses in rectal tissue associated with delayed SIV acquisition in female rhesus macaques, but the initial mechanisms leading to the induced immu...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Someone is interested in laws regarding vaccination in the United States. There is often a tension between the liberty interest and social welfare in public health, at least from many people's perspective. It is a general principle that competent adults cannot be compelled to undergo any medical procedure against their will. Adults can decide to check out of the hospital against medical advice, or to treat their cancer with coffee enemas rather than surgery and chemotherapy, and the state does not get involved. As for people who are ruled not competent, that's a whole other discussion, but I will point out that a judge has...
Source: Stayin' Alive - Category: American Health Source Type: blogs
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