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RheumShorts: New Knees, Lupus Med Switches (CME/CE)

(MedPage Today) -- The news in rheumatology this week included reports on knee replacements in the Dominican Republic, outcomes with scleroderma overlap disease, and reasons for switching maintenance therapy in lupus.
Source: MedPage Today Geriatrics - Category: Geriatrics Source Type: news

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CONCLUSIONS: This case series suggests that the hormonal modification as part of gender transition may be relevant in development of SSc. No further conclusions can be drawn on the continuation or not of HT. PMID: 29465362 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
AbstractThe present study examines the concept of illness identity, the degree to which a chronic illness is integrated into one ’s identity, in adults with a chronic illness by validating a new self-report questionnaire, the Illness Identity Questionnaire (IIQ). Self-report questionnaires on illness identity, psychological, and physical functioning were assessed in two samples: adults with congenital heart disease (22–78  year old;n = 276) and with multisystem connective tissue disorders (systemic lupus erythematosus or systemic sclerosis; 17–81 year old;n = 241). Th...
Source: Journal of Clinical Psychology in Medical Settings - Category: Psychiatry & Psychology Source Type: research
Contributors : Eleni Chouri ; Marzia Rossato ; Timothy R RadstakeSeries Type : OtherOrganism : Homo sapiensTo investigate the miRNA signature in the serum of systemic sclerosis (SSc) patients. The levels of 758 miRNAs were evaluated in the serum of 26 SSc patients as compared to 9 healthy controls by using an Openarray platform. Patients fulfilling the ACR/EULAR 2013 classification criteria were classified in relation to the extent of skin fibrosis as limited cutaneous (lcSSc) or diffuse cutaneous SSc (dcSSc); patients fulfilling the classification criteria without skin fibrosis will be referred to as non-cutaneous SSc (nc...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research
Conclusion Both SLE and SSc patients with longstanding disease had significant reduction in all stages of TDI that maintained stable over a 2-year period. Olfactory dysfunction was associated with age, inflammation and hippocampi and amygdalae volumes. In SLE, additional association with anti-P, anxiety and depression symptoms was observed.
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
AbstractGuidelines or recommendations help to provide uniform standards in medical practice. The development of guidelines requires adherence to pre-defined norms prescribed by different international organizations such as the European League against Rheumatism (EULAR). We searched Pubmed and LILACS to identify published papers in five major rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, spondyloarthropathies, osteoarthritis, and scleroderma) from different countries based on their economic prosperity and could find a lack of published literature from most economically weaker regions. Similarly, pu...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Conditions:   Lupus Erythematosus;   Scleroderma;   Rheumatoid Arthritis;   Gougerot-Sjögren Disease;   Autoimmune Thrombocytopenia Interventions:   Other: blood sample;   Other: urine sample;   Other: food questionnaire Sponsor:   University Hospital, Bordeaux Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study aimed to review and compare the diagnostic accuracy of the screening enzyme immunoassay (SEIA) and indirect immunofluorescence (IIF) as anti-nuclear antibody (ANA) screening assays for patients with systemic rheumatic diseases (SRDs), including systemic lupus erythematosus (SLE), Sj ögren's syndrome (SS), and systemic sclerosis (SSc).
Source: Seminars in Arthritis and Rheumatism - Category: Rheumatology Authors: Source Type: research
ConclusionIn the first multicenter prospective cohort of juvenile SSc patients in North America, disease burden was large: multiā€organ manifestations were common, and functional disability was greater than other childhood rheumatic diseases. Gastrointestinal involvement had the greatest impact on quality of life.This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Publication date: Available online 31 January 2018 Source:Canadian Journal of Cardiology Author(s): Reto D. Kurmann, Rekha Mankad Women have a higher prevalence of several inflammatory rheumatologic conditions. These include systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) to name a few. These conditions are all associated with higher rates of cardiovascular (CV) morbidity and mortality, which is driven primarily by atherosclerotic heart disease. Traditional risk factors are important considerations in the assessment of CV risk in the rheumatologic patient; however, these factors...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Pathogenic drivers of the pulmonary vascular disease that results in pulmonary arterial hypertension (PAH) are currently unclear, but there are many reasons to suspect that inflammation is a major contributor. Clinically, PAH is a complication of multiple autoimmune diseases including scleroderma and systemic lupus erythematosus, suggesting dysregulated immunity can trigger the vascular disease [1–3]. PAH can also complicate several infectious diseases, including HIV and schistosomiasis, suggesting there could be off-target effects of immune upregulation which inadvertently damage the pulmonary vasculature. Patients ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Pulmonary vascular disease Editorials Source Type: research
More News: Dominican Republic Health | Geriatrics | Lupus | Rheumatology | Scleroderma