Trimethyl chitosan improves Anti-HIV effects of Atripla as a new nano-formulated drug.

Conclusion; The result showed that atripla-TMC conjugate does not have a significant cytotoxicity effect. Due to the higher inhibitory effect of nano-conjugate on viral replication, it can be used in lower concentration for antiviral treatment, which resulted in reduction of drug resistance and other side effects.
PMID: 27993121 [PubMed - as supplied by publisher]

Source: Current HIV Research - December 15, 2016 Category: Infectious Diseases Authors: Shohani S, Abdoli A, Khansarinejad B, Ardestani MS, Salimi-Asl M, Ghanbari M, Haj MS, Zabihollahi R, Mondanizadeh M Tags: Curr HIV Res Source Type: research