Association of Candida Species Isolated From the Dental Plaque of HIV-infected Children and Prevalence of Early Carious Lesions
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Conclusions: Empirical use of an echinocandin in critically ill patients with documented candidemia reduces mortality at 30 and 90 days significantly. Deescalation of the empirical echinocandin to fluconazole is safe and effective in fluconazole-susceptible infections.
Xiao-Yu Yu, Fei Fu, Wen-Na Kong, Qian-Kun Xuan, Dong-Hua Wen, Xiao-Qing Chen, Yong-Ming He, Li-Hua He, Jian Guo, Ai-Ping Zhou, Yang-Hong Xi, Li-Jun Ni, Yu-Feng Yao, Wen-Juan Wu
Publication date: Available online 22 February 2018 Source:EuPA Open Proteomics Author(s): Andy Awad, Pamela El Khoury, Brigitte Wex, Roy A. Khalaf We previously characterized Pga1, a Candida albicans (C. albicans) cell wall protein necessary for proper virulence, adhesion, and resistance to oxidative stress. By utilizing tandem mass spectrometry coupled with bioinformatics to investigate cell wall proteome expression in a pga1 null fourteen and 36 proteins were identified in the wild type grown under filamentous and non-filamentous conditions respectively, but were not detected in the mutant, including members of the PGA...
This study aimed to evaluate the behavior of yeasts as starter cultures for dry processed coffee. Saccharomyces cerevisiae CCMA 0543, Candida parapsilosis CCMA 0544, and Torulospora delbrueckii CCMA 0684 were separately inoculated into coffee by directly spraying the cherries on a terrace or in buckets for 16 h before sun drying. Samples were collected and analyzed by qPCR (inoculum persistence), HPLC and GC-MS. Sensory analysis was performed on the roasted coffee. All treatments directly inoculated with yeasts showed high citric and malic acid concentrations. Caffeine, chlorogenic acids and trigonelline concentrations v...
Conclusions The presence of anti-Candida and anti-inflammatory activities in Tetraglochin andina extracts give support to their traditional use for treating conditions associated with microorganism infections and inflammatory process in humans. This plant preparation could be used to design phytopharmaceutical preparations to inhibit yeast growth and moderate the inflammatory and oxidative process. Graphical abstract
ProblemIs sensitization to atopic reaction related to treatment response of recurrent Candida vulvovaginal (RVVC)? Method of the studyAnalysis of ReCiDiF trial data of optimal (OR) and non‐responders (NR) to fluconazole maintenance treatment, to explore medical history, physical status, family history, and vaginal immune response for potential sensitization to atopic reaction. ResultsSociodemographic characteristics of 33 NR women were not different from 38 OR. NR had received higher number of different treatments (mean difference 1.6 different treatments (95% CI: 0.20‐2.97), P = .03) and had more episodes of disease (P
Conclusion: Indole and Isatin affected the expression of multiple genes in the yeast to hyphal signal transduction pathway in Candida albicans. In conclusion both Isatin and Indole may represent potential anti-virulence agents against Candida albicans. Indole derivatives could be good candidates for drug repositioning.
Conclusions: AEEMC antimicrobial efficacy test results vary based on challenge microorganism, contact lenses, and MPS biocide systems. This study highlights the importance of evaluating MPSs for compatibility with lenses and lens cases.
We report the case of a 53-year-old immunocompetent female patient with a fungal spondylodiscitis infection caused byCandida glabratadiagnosed by open surgical biopsy, one-month posturosepsis.Results: Our patient withCandida glabrata was disease free in 6 months after being treated through surgical fusion at the level of C4-C5 and the use of intravenous micafungin followed by oral voriconazole for a total of 6 months.Discussion: Fungal spondylodiscitis, especially due toCandida glabrata, remains a rare condition, usually suspected in immunocompromised and elderly patients. Without appropriate diagnosis and tailored surgica...