Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period.

In conclusion, pregnancy affects S-, R-, and S/R-ketorolac disposition. This is of clinical relevance since S-ketorolac (analgesia) CL is even more increased compared to R-ketorolac CL, and S/R-ketorolac CL ratio is higher following delivery compared to postpartum period or to healthy female volunteers. PMID: 27968707 [PubMed - as supplied by publisher]
Source: Bosnian Journal of Basic Medical Sciences - Category: Journals (General) Tags: Bosn J Basic Med Sci Source Type: research