Power of an Adaptive Trial Design for Endovascular Stroke Studies [Clinical Sciences]

Conclusions—These simulations, based on real-world patient data, indicate that adaptive subgroup selection has merit in endovascular stroke trials as it substantially increases power when the treatment effect differs among subgroups in a predicted pattern.

Source: Stroke - November 27, 2016 Category: Neurology Authors: Maarten G. Lansberg, Ninad S. Bhat, Sharon D. Yeatts, Yuko Y. Palesch, Joseph P. Broderick, Gregory W. Albers, Tze L. Lai, Philip W. Lavori Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research