Myeloperoxidase –Antineutrophil Cytoplasmic Antibody (ANCA)–Positive Granulomatosis With Polyangiitis (Wegener's) Is a Clinically Distinct Subset of ANCA‐Associated Vasculitis: A Retrospective Analysis of 315 Patients From a German Vasculitis Referral Center

ConclusionPatients with MPO‐ANCA−positive GPA show significantly different clinical courses compared to those with PR3‐ANCA−positive GPA or MPO‐ANCA−positive MPA, which should be considered in their clinical management. Classification according to ANCA specificity may improve the evaluation of relapse risk.

Source: Arthritis and Rheumatism - November 27, 2016 Category: Rheumatology Authors: Jan H. Schirmer, Marvin N. Wright, Kristine Herrmann, Martin Laudien, Bernhard N ölle, Eva Reinhold‐Keller, Jan P. Bremer, Frank Moosig, Julia U. Holle Tags: Vasculitis Source Type: research