An update on the clinical management of cutaneous molluscum contagiosum.

An update on the clinical management of cutaneous molluscum contagiosum. Skin Therapy Lett. 2014 Apr;19(2):5-8 Authors: Nguyen HP, Tyring SK Abstract Molluscum contagiosum is a poxvirus infection of the skin that is commonly observed in children. The molluscum contagiosum virus (MCV) expresses several gene-products that are involved in its pathogenesis and evasion of the host immune system. MCV can be transmitted both to other sites of the body and to other individuals through direct physical contact as well as fomites. While diagnosis is generally straightforward clinically, management of molluscum contagiosum is controversial. Several treatment options are available for the destruction of individual lesions, but there is insufficient evidence for therapeutic intervention being any more effective than natural, spontaneous resolution. Complex cases, such as infection occurring in immunocompromised patients and in mucocutaneous sites, require an alternative approach to management. Molluscum contagiosum continues to represent a burden on children and parents worldwide. PMID: 24740746 [PubMed - in process]
Source: Skin Therapy Letter - Category: Dermatology Authors: Tags: Skin Therapy Lett Source Type: research

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Homœopathic Links 2019; 32: 230-234 DOI: 10.1055/s-0040-1701662Molluscum contagiosum (MC) is a benign skin condition having peculiar pearly white or pink lesions. This is considered to be a very contagious disease, common in children of low socioeconomic group. Conventionally, local removal of lesions is the primary choice of treatment, commonly cryotherapy. This is a report of three cases suffering from MC for a variable period, treated with individualised homoeopathic treatment. The rationale of this report reflects the effective management of such cases with homoeopathy. [...] Thieme Medical and Scientific Publish...
Source: Homoeopathic Links - Category: Complementary Medicine Authors: Tags: Case Report Source Type: research
AbstractPurpose of ReviewMolluscum contagiosum (MC) is a self-limited cutaneous viral infection that most commonly affects children and immunocompromised populations. This review provides an update on the clinical manifestations, risk, diagnosis, treatment, and prevention of this frequently encountered infection.Recent FindingsA recent Cochrane review concluded that there is insufficient evidence to establish the superiority of any specific treatment modality or to confirm that active intervention is superior to benign neglect (van der Wouden JC et al., Cochrane Database Syst Rev 5:CD004767, 2017). Interim pilot study data...
Source: Current Dermatology Reports - Category: Dermatology Source Type: research
Authors: Meyer D, Smit DP Abstract Both infective and neoplastic eyelid and orbital conditions in human immunodeficiency virus (HIV) infected patients are often the result of opportunistic or co-infections (OI). In most cases, these clinical findings in younger patients alert the physician to suspected underlying HIV infection. When the eyelids and periorbital skin are primarily involved in OI with varicella-zoster virus it is called Herpes Zoster Ophthalmicus. Co-infection with a Pox virus manifests as molluscum contagiosum eruptions. Orbital cellulitis is secondary to various organisms (Mycobacterium tuberculosis...
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
CONCLUSIONS: Atopic dermatitis patients had higher odds of multiple bacterial, viral, fungal, and sexually transmitted skin infections. PMID: 32049716 [PubMed - as supplied by publisher]
Source: Dermatitis - Category: Dermatology Authors: Tags: Dermatitis Source Type: research
AbstractVariants inMAGT1 have been identified as the cause of an immune deficiency termed X-linked immunodeficiency with magnesium defect, Epstein-Barr virus (EBV) infection and neoplasia (XMEN) disease. Here, we describe 2 cases of XMEN disease due to novel mutations inMAGT1, one of whom presented with classical features of XMEN disease and another who presented with a novel phenotype including probable CNS vasculitis, HHV-8 negative multicentric Castelman disease and severe molluscum contagiosum, thus highlighting the clinical diversity that may be seen in this condition. Peripheral blood immunophenotyping of these 2 pat...
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
ConclusionsThis case demonstrates some of the various intraoral and extraoral presentations of HIV infection, including NUP, fingernail hyperpigmentation, cervical lymphadenopathy, molluscum contagiosum, and pseudomembranous candidiasis. Although the patient's chief complaint was painful gingivae, the presence of other lesions led to a suspected, and later confirmed, diagnosis of HIV infection. Therefore, it is important that clinicians know the various manifestations of HIV infection, especially in patients who are undiagnosed. The possibility of undiagnosed HIV infection should be suspected, and a referral for appropriat...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Molluscum contagiosum is a viral infectious disease that mainly affects children and young adults. The lesions occur predominantly in the skin and genitalia; involvement of the oral soft tissues is uncommon. Oral lesions occur most frequently on the lips, tongue, and buccal mucosa. A 20-year-old woman presented with pink, smooth, sessile, and painless papules on the upper lip with an evolution time of 2 weeks. The conduct was excisional biopsy of the lesion and histopathologic examination. The histologic slices revealed a well-defined epithelial proliferation, with areas of central depression, filled with keratinocytes altered by the virus.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
We report this case to demonstrate that reactive CD30+ infiltrate associated with molluscum contagiosum can be mistaken for T-cell lymphomas and patients should be reassured in these cases.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
WEST CHESTER, Pa., Nov. 27, 2019 (GLOBE NEWSWIRE) -- Verrica Pharmaceuticals Inc. (“Verrica”) (Nasdaq: VRCA), a medical dermatology company, today announced that its New Drug Application (NDA) for VP-102 (cantharidin 0.7% Topical...
Source: Drugs.com - New Drug Applications - Category: Drugs & Pharmacology Source Type: news
Authors: Pérez Dieste JM, Castroviejo Bolíbar M, Gordillo Vélez CH, Sánchez Servate C, Garrido Serrano N PMID: 31740279 [PubMed - as supplied by publisher]
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
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