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Arthritis drug Celebrex may help treat depression, researchers say

Ryan MaassMAYWOOD, Idaho, Nov. 11 (UPI) -- Researchers have found that the arthritis drug celecoxib, often marketed as Celebrex, can help make anti-depression medication more effective.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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The objective of this study is to describe aspects of health-related quality of life (HRQOL) in Mexican patients with antineutrophil cytoplasmic-associated vasculitis (AAV). Cross-sectional comparison study includes patients with established AAV and a comparison group with rheumatoid arthritis (RA), chronic kidney disease (CKD), and healthy subjects. Variables considered were: socio-demographic data, comorbidities, laboratory, disease activity, damage, and Physician ’s and Patient’s Global Assessment (PhGA and PtGA). The following measurements were done: Pittsburg sleep quality index, Multidimesional Fatigue In...
Source: Rheumatology International - Category: Rheumatology Source Type: research
ConclusionResults support the efficacy of an iCBT program (requiring no face‐to‐face contact) for depression in individuals with comorbid depression and OA of the knee. Importantly, the benefits of the program extended beyond reduced depressive symptoms and distress to include increased self‐efficacy and improved pain, stiffness, and physical function at followup.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Conclusions Important other autonomy support for physical activity may hold positive consequences for LPA engagement and related mental health states in RA, independent of the negative effects of lower-limb functional disability.
Source: Mental Health and Physical Activity - Category: Psychiatry & Psychology Source Type: research
On Tuesday 5th December, Arthritis Research UK held our first Scottish parliamentary reception in Holyrood as a newly merged charity to highlight the prevalence and impact of arthritis in Scotland. Kindly sponsored by Rona MacKay MSP, the event was attended by 8 of Members of Scottish Parliament (MSPs) who came to find out about how arthritis can affect people with musculoskeletal conditions.MSPs spoke to people living with arthritis, tried our gloves which simulate the mobility restrictions arthritis can cause, as well as received exclusive data on how many people in their local area may have certain forms of arthritis.Ca...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
ConclusionProvision of pedometers, with and without providing step targets, was successful in increasing activity levels and decreasing fatigue in this sample of individuals with RA.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Tags: Original Article Source Type: research
We describe comorbidity, analytical, functional and radiological data and mortality.Results: We study 31 patients, 11 males, age of 70 ± 9.4 years, 18/31 were former or smokers. RA was diagnosed 7,9 ± 8,6 years before the ILD. ILD was diagnosed before RA in 10%. The BMI was 27 ± 4. Rheumatoid factor (RF) and anti-ccp were positive in 86% (25/29) and 77% (20/26) with median values of 280 ± 376 and 751 ± 821. One patient had both antibodies negative. CRP and the ESR median values were 2.5 ± 6.6 and 42 ± 23, respectively. Concomitant diseases were, 19/31 (61%) hypertension, 5/3...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Diffuse Parenchymal Lung Disease Source Type: research
Conclusions MSK conditions are salient, and a likely key cause of impaired subjective well-being and functioning among older slum populations in SSA. Further research on determinants and consequences of such conditions in older slum populations is required to inform debate on responses to MSK as part of efforts to reorient SSA health systems to aging and to improve slum health.
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusion MO has emerged as a good source of traditional medicines. Some uses of this plant in traditional medicines have been validated by pharmacological investigations. However, the molecular mechanism, structure-activity relationship, and potential synergistic and antagonistic effects of its multi-components such as polysaccharides, oligosaccharides, anthraquinones and iridoid glycosides need to be further elucidated, and the structural feature of polysaccharides also need to be further clarified. Sophisticated analytical technologies should be developed to comprehensively evaluate the quality of MO based on HPLC-fing...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
AbstractPurposeThe reasons for the comorbidity between depressed mood and poor sleep are not well understood.MethodParticipants were 5172 adults aged 50  years and older from the English Longitudinal Study of Ageing. Sleep was measured via self-report and depressive symptoms using the Centre for Epidemiological Studies Depression scale.ResultsGreater depressive symptoms and sleep complaints were associated with female sex, non-cohabitation, relative poverty, smoking, infrequent physical activity, infrequent alcohol consumption, higher body mass index (BMI), diagnosis of hypertension, coronary heart disease, diabetes/h...
Source: International Journal of Behavioral Medicine - Category: Psychiatry Source Type: research
p Abstract OBJECTIVE Depression and anxiety have been demonstrated to have negative impacts on outcomes after spine surgery. In patients with cervical deformity (CD), the psychological and physiological burdens of the disease may overlap without clear boundaries. While surgery has a proven record of bringing about significant pain relief and decreased disability, the impact of depression and anxiety on recovery from cervical deformity corrective surgery has not been previously reported on in the literature. The purpose of the present study was to determine the effect of depression and anxiety on patients' recovery...
Source: Neurosurgical Focus - Category: Neurosurgery Authors: Tags: Neurosurg Focus Source Type: research
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