An association between ABO group and HLA antibody detection.

CONCLUSION: Centers using the ELISA may have a higher rate of permanent deferral from plateletpheresis donation among group O female donors. Although the reasons for the higher rate of reactivity on Class I ELISA testing are unknown, this could result from test system characteristics or differences in group O donor antibody strength or specificity.
PMID: 27807878 [PubMed - as supplied by publisher]

Source: Transfusion - November 2, 2016 Category: Hematology Authors: Dunbar NM, Yazer MH, Bravo MD, Kamel HT, Gorlin J, Norris PJ, Williamson PC, Vassallo RR, Biomedical Excellence for Safer Transfusion (BEST) Collaborative Tags: Transfusion Source Type: research