Adaptive Cross-Resistance to Aminoglycoside Antibiotics in Pseudomonas aeruginosa Induced by Topical Dosage of Neomycin

Conclusions: Our findings suggest thatP. aeruginosa can survive in the presence of neomycin with a concentration typically used in topical dosage forms, and that the acquired adaptive resistance is persistent and is accompanied by cross-resistance to other aminoglycosides.Chemotherapy 2017;62:121-127
Source: Chemotherapy - Category: Cancer & Oncology Source Type: research