The Relationship between Urinary Renin Angiotensin System Markers, Renal and Vascular Function in Adolescents with Type 1 Diabetes.

CONCLUSIONS: Otherwise healthy adolescents with T1D exhibit higher levels of urinary RAAS components compared to HC. While levels of all urinary RAAS components correlate with HbA1c in T1D, only urinary angiotensinogen and ACE activity correlate with ACR, suggesting that these factors reflect an intermediary pathogenic link between hyperglycemia and albuminuria within the normal range. PMID: 27733369 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27733369?dopt=Abstract

Source: Am J Physiol Renal P... - October 11, 2016 Category: Urology & Nephrology Authors: Burns KD, Lytvyn Y, Mahmud FH, Daneman D, Deda L, Dunger DB, Deanfield JE, Dalton RN, Elia Y, Har R, Van JA, Bradley TJ, Slorach C, Hui W, Xiao F, Zimpelmann J, Mertens L, Moineddin R, Reich HN, Sochett EB, Scholey JW, Cherney DZ Tags: Am J Physiol Renal Physiol Source Type: research

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