Management of chronic cough in children

Advice on managing chronic cough in children, understanding symptoms, possible causes and suitable investigations.
Source: GP Online Education - Category: Primary Care Tags: Paediatrics Source Type: news

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Authors: Mian A, Singal AK, Bakhshi S, Sood R, Vikram NK, Ray A Abstract A 21-year old female, recently diagnosed with osteosarcoma of right humerus, presented to the emergency with history of fever, productive cough, chest pain and progressive respiratory distress for six days. Initial investigations suggested pneumonia but she did not respond to parenteral antibiotics. CT pulmonary angiogram revealed bilateral pulmonary artery embolism. Thrombolysis was performed using alteplase, which failed to improve the clinical condition. In view of underlying malignancy, a possibility of tumour-embolism was considered and s...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Sharma R, Mahajan SK, Singh B, Raina R, Kanga A Abstract Aims: To study predictors of severity in patients of scrub typhus admitted in a tertiary care hospital. Material and Methods: Total 92 patients of scrub typhus were included in the study. The diagnosis was established by presence of IgM antibodies by Indirect Immunofluorescence Assay (IFA) test which is currently the reference standard for the diagnosis of scrub typhus. The clinical and laboratory profile, course in hospital, and outcome were documented. Factors associated with severe disease were analyzed. Observations: Fever (100%), cough (...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
In this study, we aimed to investigate the protective effects and underlying antitussive mechanisms of Suhuang on pulmonary function in ovalbumin (OVA)-induced CVA rats. Administration (i.g.) of Suhuang significantly alleviated pulmonary damage and dysfunction. Suhuang improved ER stress and PKCε translocation via regulation of Ca2+ trafficking. Suhuang also inhibited NLRP3 inflammasome activation, as evidenced by disrupting the assembly of NLRP3 inflammasome and reducing the expression of cleaved caspase-1, and decreased IL-1β secretion. Besides, it’s identified that TXNIP induction and RIP1-RIP3-Drp1 p...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Abstract The allergic airway diseases, including chronic rhinosinusitis (CRS), asthma, allergic bronchopulmonary mycosis (ABPM) and many others, comprise a heterogeneous collection of inflammatory disorders affecting the upper and lower airways and lung parenchyma that represent the most common chronic diseases of humanity. In addition to their shared tissue tropism, the allergic airway diseases are characterized by a distinct pattern of inflammation involving the accumulation of eosinophils, type 2 macrophages, innate lymphoid cells type 2 (ILC2), IgE-secreting B cells, and T helper type 2 (Th2) cells in airway t...
Source: Advances in Immunology - Category: Allergy & Immunology Authors: Tags: Adv Immunol Source Type: research
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Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
A large cross-sectional study of UK prescribing data found that the duration of antibiotic prescriptions for common infections in primary care frequently exceeded national guideline recommendations. The most common reason for antibiotic prescribing was for respiratory infections, and more than 80% of prescriptions for acute cough and bronchitis, acute sore throat, acute otitis media and acute exacerbations of COPD were for longer than recommended. Substantial reductions in antibiotic exposure can be achieved by prescribing antibiotics in line with NICE and Public Health England guidance on managing common infections.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Listen to an audio podcast of the January 11, 2018 FDA Drug Safety Communication requiring safety labeling changes for prescription cough and cold medicines containing codeine or hydrocodone to limit the use of these products to adults 18 years and older because the risks of these medicines outweigh their benefits in children younger than 18.
Source: FDA Drug Safety Podcasts - Category: Drugs & Pharmacology Authors: Source Type: podcasts
The diagnosis of pertussis in clinical practice continues to be a challenge worldwide as the symptoms are variable. We aimed to determine the prevalence of pertussis in Chinese children irrespective of cough d...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research
Cough is a common and chief complaint in primary care. Chronic cough, which is defined as cough lasting for a duration of 4 or more weeks by the American College of Chest Physicians Guidelines (Chang et al., 2017), requires medical attention; it is important to determine the etiology of chronic cough in infants and children. Although chronic cough can be commonly attributed to airway disorders and infectious diseases, it is important to consider less-common diagnoses and use appropriate pediatric guidelines when diagnosing and treating the underlying cause (Bergamini, Kantar, Cutrera,&Italian Pediatric Cough Interest G...
Source: Journal of Pediatric Health Care - Category: Pediatrics Authors: Tags: Case Report Source Type: research
Conclusions: Solid conclusions regarding the respiratory consequences of regular cannabis smoking are difficult to make due to a relative paucity of literature, confounding by concurrent tobacco smoking and reports of conflicting outcomes. Additional well-controlled clinical studies on the pulmonary consequences of habitual cannabis use are needed. PMID: 31298945 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - Category: Addiction Authors: Tags: Am J Drug Alcohol Abuse Source Type: research
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