Adenosine A2A Receptor Promotes Collagen Type III Synthesis Via β‐Catenin Activation in Human Dermal Fibroblasts

Conclusions and ImplicationsA2AR stimulation promotes Col3 synthesis via canonical and non‐canonical β‐catenin activation, consistent with the role of A2AR in dermal fibrosis and scarring.

Source: British Journal of Pharmacology - August 31, 2016 Category: Drugs & Pharmacology Authors: Gibran Shaikh, Jin Zhang, Miguel Perez ‐Aso, Aranzazu Mediero Munoz, Bruce Cronstein Tags: RESEARCH PAPER Source Type: research