The Effect of Early Goal-Directed Therapy on Outcome in Adult Severe Sepsis and Septic Shock Patients: A Meta-Analysis of Randomized Clinical Trials

This meta-analysis shows, a nonsignificant trend toward reduction in the longest all-cause mortality in patients resuscitated with EGDT. However, EGDT significantly reduced intensive care unit mortality in severe sepsis and septic shock patients. TSA indicated a lack of firm evidence for the results. More powered, randomized controlled trials are needed to determine the effects.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news