Immunomodulators in the Treatment of Nasal Polyposis.

Immunomodulators in the Treatment of Nasal Polyposis.
Adv Otorhinolaryngol. 2016;79:103-113
Authors: Halderman AA, Lane AP
Abstract
The inflammatory mechanisms that contribute to chronic rhinosinusitis with nasal polyps (CRSwNP) are complex. In the past, medical options for treating CRSwNP have been limited. Emerging classes of immunomodulators such as omalizumab, anti-leukotrienes, anti-IL-4, anti-IL-5, and recognition of the modulating effects of macrolides have shown promising results in the treatment of CRSwNP. Ultimately, large randomized controlled trials are necessary to establish the efficacy of these medications but for now, the area of medical immunomodulators remains an exciting frontier.
PMID: 27466852 [PubMed - as supplied by publisher]

Source: Advances in Oto-Rhino-Laryngology - July 29, 2016 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research