Current and Emerging Surgical Therapies for Severe Pediatric Epilepsies

The use of epilepsy surgery in various medically-resistant epilepsies is well-established. For patients with intractable pediatric epilepsy, the role of intracranial electrodes, resective surgery, hemispherectomy, corpus callosotomy, neurostimulation, and multiple subpial transections continues to be very effective in select cases. Newer treatment and diagnostic methods include laser thermal ablation, minimally invasive surgeries, stereo electroencephalogram (EEG), changes in electrocorticography, and other emerging techniques.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research

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Publication date: June 2020Source: Epilepsy &Behavior, Volume 107Author(s): Andreu Massot-Tarrús, Kevin P. White, Seyed Reza Mousavi, Susan Hayman-Abello, Brent Hayman-Abello, Seyed M. Mirsattari
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
In conclusion; Beta-Propeller Protein Associated Neurodegeneration should be considered as an option in the diagnosis of female patients with clinical findings of epilepsy, growth retardation and autism, with unspecified etiology. PMID: 32253879 [PubMed - in process]
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
In this report, we present a 5-year-old boy who had dysmorphic features, hypotonia, developmental and mental delay, epileptic spasms, recurrent apnea and respiratory failure that led to the diagnosis of an unreported mutation of a rare form of CDG-Ix. This mutation in the STT3B gene affects the catalytic subunit of the oligosaccharyltransferase and the recipient substrate properties, which in part have the same functions in N-glycosylation. A novel homozygous mutation in the STT3B presence of c.38C> G that encodes p.S13W (p.Ser13Trp) was detected with next generation sequencing. The CDG clinical spectrum can be unusual,...
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
In conclusion; Beta-Propeller Protein Associated Neurodegeneration should be considered as an option in the diagnosis of female patients with clinical findings of epilepsy, growth retardation and autism, with unspecified etiology. PMID: 32253874 [PubMed - in process]
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
A Colorado girl with a rare form of epilepsy whose recovery inspired the name of a medical marijuana oil that drew families to the state has died
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Charlotte Figi, a child with a catastrophic type of epilepsy who went on to inspire a CBD movement, passed away Tuesday at age 13.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Conclusion: Several spots with differential expression were observed by comparing patients with ES against the PNES groups, which could be potential biomarkers of the disease. Damage to the blood-brain barrier is the most important difference between the two groups, thus identifying total protein changes offers a key to the future of differentiating ES and PNES patients. PMID: 32259116 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - Category: Emergency Medicine Authors: Tags: Arch Acad Emerg Med Source Type: research
Conclusions: The study revealed that there was a higher prevalence of vitamin D3 insufficiency in epileptic children receiving valproate monotherapy compared with healthy children. Vitamin D3 supplementation should be given to all epileptic children even before initiation of anti-epileptic drugs. PMID: 32259112 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - Category: Emergency Medicine Authors: Tags: Arch Acad Emerg Med Source Type: research
Research into cancer, heart disease, HIV, MS, Alzheimer ’s, gene therapy, opioid addiction, epilepsy, blindness — all abruptly stopped in mid-March.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
(COLORADO SPRINGS, Colo.) — A girl with a rare form of epilepsy whose recovery inspired the name of a medical marijuana oil that drew families of children with similar health problems to Colorado for treatment has died, according to the non-profit organization founded by her mother. No cause of death was given for Charlotte Figi, 13, in the Facebook announcement from the non-profit group Realm of Caring. However, a post on her mother’s Facebook page said Charlotte was recently hospitalized because she had not recovered from a virus that had hit her whole family. Calls to relatives and the foundation for additio...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized News Desk remembrance wire Source Type: news
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