Glomerular disease: Membranous nephropathy and the Henle –Koch postulates
Nature Reviews Nephrology 12, 447 (2016).
doi:10.1038/nrneph.2016.86
Authors: Hans-Joachim Anders & Claudio Ponticelli
Antibodies against several podocyte antigens have evolved as markers of diagnosis, disease activity, and prognosis in membranous nephropathy, but their pathogenic role remains debated. Detailed work-up of two cases of primary and secondary membranous nephropathy now supports the concept that thrombospondin type-1 domain-containing 7A autoantibodies are pathogenic.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Hans-Joachim Anders Claudio Ponticelli Tags: News and Views Source Type: research
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