Glomerular disease: Membranous nephropathy and the Henle –Koch postulates

Nature Reviews Nephrology 12, 447 (2016). doi:10.1038/nrneph.2016.86 Authors: Hans-Joachim Anders & Claudio Ponticelli Antibodies against several podocyte antigens have evolved as markers of diagnosis, disease activity, and prognosis in membranous nephropathy, but their pathogenic role remains debated. Detailed work-up of two cases of primary and secondary membranous nephropathy now supports the concept that thrombospondin type-1 domain-containing 7A autoantibodies are pathogenic.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: News and Views Source Type: research