Regioselctive Thiocyanation of Aromatic and Heteroaromatic Compounds Using a Novel Brønsted Acidic Ionic Liquid.

Regioselctive Thiocyanation of Aromatic and Heteroaromatic Compounds Using a Novel Brønsted Acidic Ionic Liquid.
Comb Chem High Throughput Screen. 2016 Jul 9;
Authors: Sheikholeslami-Farahani F, Rezayati S, Hossaini Z, Hajinasiri R, Abada SA
Abstract
A convenient procedure for preparation 1-(1-Propylsulfonic)-3-methylimidazolium thiocyanate as a novel Brønsted acidic ionic liquid thiocyanation agent and highly efficient heterogeneous catalytic is describes. This catalyst is used in regioselective thiocyanation of indoles, anilines, pyrroles and their derivatives (aromatic and heteroaromatic organic compounds) in the presence of H2O2 as a mild and oxidant in EtOH:H2O (1:1 v/v). These reactions performed under mild and simple conditions and give regioselective products in high yields and short reaction time.
PMID: 27396916 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - July 8, 2016 Category: Chemistry Authors: Sheikholeslami-Farahani F, Rezayati S, Hossaini Z, Hajinasiri R, Abada SA Tags: Comb Chem High Throughput Screen Source Type: research