A comparative planning study for lung SABR between tri-Co-60 magnetic resonance image guided radiation therapy system and volumetric modulated arc therapy.

A comparative planning study for lung SABR between tri-Co-60 magnetic resonance image guided radiation therapy system and volumetric modulated arc therapy. Radiother Oncol. 2016 Jul 8; Authors: Park JM, Park SY, Kim HJ, Wu HG, Carlson J, Kim JI Abstract BACKGROUND AND PURPOSE: To compare the plan quality of tri-(60)Co magnetic-resonance image-guided radiation therapy (IGRT) to that of volumetric modulated arc therapy (VMAT) for lung stereotactic ablative radiotherapy (SABR). MATERIALS AND METHODS: A total of 22 patients with lung tumors located in the lower lobe were selected retrospectively. For each patient, VMAT plans with linac and intensity-modulated radiation therapy (IMRT) plans with the tri-(60)Co system were generated with prescription doses of 60Gy (daily dose=15Gy). For both plan types, identical CT image sets and structures were used, with the exception of planning target volumes (PTV). The PTV for VMAT was generated from the internal target volume (ITV) while the PTV for the tri-(60)Co system was generated from the gross tumor volume (GTV). Clinically relevant dose-volumetric parameters were calculated and analyzed. RESULTS: The average PTV volumes of tri-(60)Co plans and VMAT plans were 10.5±12.3cc vs. 27.2±23.5cc, respectively (p
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research

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Proton Beam Therapy (PBT) is dosimetrically superior to Intensity Modulated Radiation Therapy (IMRT) in sparing critical organs in esophageal cancer (EC) patients (pts) treated with chemoradiation therapy (CRT). The extent to which better dosimetry translates into clinical benefit is not well established. We conducted a randomized trial to compare PBT to IMRT in terms of total toxicity burden (TTB) and progression free survival (PFS) time.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
Four years ago, Varian’s Applied Research Team, a group separate from its research and development unit, began looking at how to incorporate artificial intelligence into cancer therapy. The team’s hard work has resulted in the development of Ethos, an AI-driven holistic solution designed to increase the efficiency of radiotherapy. MD+DI spoke with Chris Toth, president of Varian Oncology Systems ahead of Ethos’ launch at the American Society for Radiation Oncology [ASTRO] annual meeting in Chicago held this week. Ethos is an Adaptive Intelligence solution. T...
Source: MDDI - Category: Medical Devices Authors: Tags: Imaging Source Type: news
Conclusions: VMAT plan can reduce the risk of secondary malignancy while treating different sites of cancer. VMAT is the most appropriate technique than IMRT, especially in the treatment of large tumor volume. Special attention has to be given, especially while treating women and children.
Source: Journal of Medical Physics - Category: Physics Authors: Source Type: research
N V. N Madhusudhana Sresty, A Krishnam Raju, B Nagarjuna Reddy, VC Sahithya, Yakub Mohmd, G Deleep Kumar, T Anil Kumar, Tasneem Rushdi, S Aparna, G Durga Prasad, Harjot Kaur BajwaJournal of Medical Physics 2019 44(3):222-227TomoTherapy® is a modern radiation treatment technique in which intensity-modulated radiation therapy (IMRT) is delivered in helical fashion. A two-dimensional (2D) array which has been existing for IMRT patient-specific quality assurance (PSQA) verifications for many years is I'MatriXX. Our objectives were to validate this I'MatriXX and to evaluate it for different patient sites and fracti...
Source: Journal of Medical Physics - Category: Physics Authors: Source Type: research
ConclusionsThe commissioning and validation of dosimetry was performed with the help of various fields, MLC patterns and complex treatment plans. The present study also evaluated the efficiency of the 3D dosimetry system for the QA of complex treatment plans.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
CONCLUSION: There is increasing variation among group practices in the use of conservative management for prostate cancer. This underscores the need for a better understanding of practice-level factors that influence prostate cancer management. PMID: 31509481 [PubMed - as supplied by publisher]
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ConclusionThe present study showed large and systematic differences in doses calculated by AAA and Acuros Dm, m. Therefore, further investigation and clarification are needed about which dose reporting mode should be used.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Abstract The aim of this study was to report a single-institution experience and commissioning data for Elekta VersaHD linear accelerators (LINACs) for photon beams in the Eclipse treatment planning system (TPS). Two VersaHD LINACs equipped with 160-leaf collimators were commissioned. For each energy, the percent-depth-dose (PDD) curves, beam profiles, output factors, leaf transmission factors and dosimetric leaf gaps (DLGs) were acquired in accordance with the AAPM task group reports No. 45 and No. 106 and the vendor-supplied documents. The measured data were imported into Eclipse TPS to build a VersaHD beam mode...
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research
Conclusion: The mean QF based on UPI was found to be close to unity, which correlates with being a better IMRT plan. The present study suggested the existence of a moderate correlation between the calculated NTCP values and their respective severities of the organ at risk (OAR’s). Accelerated IMRT with chemotherapy is a clinically feasible option in the treatment of locally advanced head and neck squamous cell carcinoma (HNSCC) with encouraging initial tumor response and acceptable acute toxicities. PMID: 31450921 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
CONCLUSIONSCoverage guidelines for IMRT, SRS, SABR, and PBT vary across 5 major insurance providers and may be substantially discordant when compared to ASTRO coverage guidelines. There remain several specific areas where ongoing and future dialogue between ASTRO, payers, and policymakers remains essential.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
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