Severe Sepsis, Septic Shock Associated With ChikungunyaSevere Sepsis, Septic Shock Associated With Chikungunya

Septic shock and severe forms of sepsis have been identified as potential complications of chikungunya virus infection. Emerging Infectious Diseases
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Infectious Diseases Journal Article Source Type: news

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AbstractSouth Texas has experienced local transmission of Zika virus and of other mosquito-borne viruses such as chikungunya virus and dengue virus in the last decades. Using a mosquito surveillance program in the Lower Rio Grande Valley (LRGV) and San Antonio, TX, from 2016 to 2018, we detected the presence of an insect-specific virus, cell fusing agent virus (CFAV), in theAedes aegypti mosquito population. We tested 6,326 females and 1,249 males from the LRGV and 659 females from San Antonio for CFAV by RT-PCR using specific primers. Infection rates varied from 0 to 261 per 1,000 mosquitoes in the LRGV and 115 to 208 per...
Source: Archives of Virology - Category: Virology Source Type: research
Authors: Mbanje C, Mungazi SG, Muchuweti D, Mazingi D, Mlotshwa M, Maunganidze AJV Abstract BACKGROUND: Ileo-sigmoid knotting is a rare cause of intestinal obstruction with a rapidly progressive course, for which expedient surgical intervention is required to prevent mortality. The aim of this study was to determine the characteristics, presentation, morbidity and mortality associated with ileo-sigmoid knotting at Parirenyatwa Group of Hospitals (PGH). To determine the preoperative diagnostic precision and management patterns of ileo-sigmoid knotting cases at PGH. METHODS: A retrospective analysis was performed...
Source: South African Journal of Surgery - Category: Surgery Tags: S Afr J Surg Source Type: research
The objective of our multicenter prospective study was to assess the performances of the different major...
Source: Annals of Intensive Care - Category: Intensive Care Authors: Tags: Research Source Type: research
AbstractObjectivesThe aim of this trial is to identify the effect of ambulatory treatment in early COVID-19 disease with hydroxychloroquine on the rate of hospitalization or death in older patients above the age of 64.Trial designParallel, 2:1 randomization, double blind, placebo-controlled, multi-center trial.ParticipantsMale and female patients above the age of 64 (i.e. ≥65 years of age) with COVID-19 diagnosis confirmed by SARS-CoV2 positive throat swab (PCR). Patients can only be included within 3 days of symptom onset in ambulatory care if they consent to the study procedure and are able to adhere to the study visi...
Source: Trials - Category: Research Source Type: clinical trials
Guillain-Barré Syndrome During Ongoing Zika Virus Transmission - Puerto Rico, January 1-July 31, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(34):910-4 Authors: Dirlikov E, Major CG, Mayshack M, Medina N, Matos D, Ryff KR, Torres-Aponte J, Alkis R, Munoz-Jordan J, Colon-Sanchez C, Salinas JL, Pastula DM, Garcia M, Segarra MO, Malave G, Thomas DL, Rodríguez-Vega GM, Luciano CA, Sejvar J, Sharp TM, Rivera-Garcia B Abstract Guillain-Barré syndrome (GBS) is a postinfectious autoimmune disorder characterized by bilateral flaccid limb weakness attributable to peripheral nerve damage (1). In...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Severe sepsis and septic shock syndrome may be rare complications of chikungunya virus infection, according to a recent study in Guadeloupe. Dr. Bruno Hoen, of the department of infectious diseases,...
Source: Internal Medicine News - Category: Internal Medicine Source Type: research
A. Rollé et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Abstract There are four medical conditions characterized by high levels of ferritin, the macrophage activation syndrome (MAS), adult onset Still’ s disease (AOSD), catastrophic antiphospholipid syndrome (CAPS), and septic shock, that share similar clinical and laboratory features, suggesting a common pathogenic mechanism. This common syndrome entity is termed “the hyperferritinemic syndrome.” Here, we describe two different cases of hyperferritinemic syndrome triggered by Chikungunya fever virus infection: a 21-year-old female with SLE and a 32-year-old male patient who developed AOSD after the c...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
We describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual manifestations of the disease. Case 1 describes a 75 year-old man with rapid onset of septic shock and multi-organ failure. Cases 2 and 3 describe two patients with rapid aggressive clinical course who developed shock, severe purpuric lesions and a distinct area large of necrosis in the nasal region. Case 4 depicts a splenectomized woman with shock, generalized purpuric lesions, bullous dermatosis and acronecrosis of an upper limb. Chikungunya fever in the Western hemisphere may also associate with atypical and severe manifestations...
Source: IDCases - Category: Infectious Diseases Source Type: research
We describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual manifestations of the disease. Case 1 describes a 75 year-old man with rapid onset of septic shock and multi-organ failure. Cases 2 and 3 describe two patients with rapid aggressive clinical course who developed shock, severe purpuric lesions and a distinct area large of necrosis in the nasal region. Case 4 depicts a splenectomized woman with shock, generalized purpuric lesions, bullous dermatosis and acronecrosis of an upper limb. Chikungunya fever in the Western hemisphere may also associate with atypical and severe manifestations...
Source: IDCases - Category: Infectious Diseases Source Type: research
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