Pathogenicity of IgG in patients with IgG4-related disease

Conclusions
IgG1 and IgG4 from patients with IgG4-RD have pathogenic activities through binding affected tissues in neonatal mice.

Source: Gut - July 7, 2016 Category: Gastroenterology Authors: Shiokawa, M., Kodama, Y., Kuriyama, K., Yoshimura, K., Tomono, T., Morita, T., Kakiuchi, N., Matsumori, T., Mima, A., Nishikawa, Y., Ueda, T., Tsuda, M., Yamauchi, Y., Minami, R., Sakuma, Y., Ota, Y., Maruno, T., Kurita, A., Sawai, Y., Tsuji, Y., Uza, N., Tags: Pancreas and biliary tract, Pancreatitis Source Type: research