Complement in disease: a defence system turning offensive

Nature Reviews Nephrology 12, 383 (2016).
doi:10.1038/nrneph.2016.70

Authors: Daniel Ricklin, Edimara S. Reis & John D. Lambris
Although the complement system is primarily perceived as a host defence system, a more versatile, yet potentially more harmful side of this innate immune pathway as an inflammatory mediator also exists. The activities that define the ability of the complement system to control microbial threats

Source: Nature Reviews Nephrology - May 22, 2016 Category: Urology & Nephrology Authors: Daniel RicklinEdimara S. ReisJohn D. Lambris Tags: Review Source Type: research