Acute kidney injury: Collectin-11: a signal for complement activation

Nature Reviews Nephrology 12, 378 (2016). doi:10.1038/nrneph.2016.68 Author: Susan J. Allison Activation of complement on the cell surface is sufficient to induce cell injury leading to inflammation and cell death; however, the initiation signal that triggers complement activation in response to injury is unknown. Now, Steven Sacks and colleagues report that the soluble C-type lectin, collectin-11
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research