Comeback of an abandoned antibiotic: Trimethoprim
In less-developed countries, inexpensive and well-tolerated antibiotics for therapy of streptococcal infections are often not available. Scientists have discovered that trimethoprim may provide an option. Contrary to a long-held belief, the bacteria are not generally resistant to this agent. In their latest publication the scientists demonstrated three pathways for the development of resistance -- meaning that streptococci can easily become resistant to the antibiotic and pass on this trait quickly.
Authors: Lecuit M PMID: 32217166 [PubMed - as supplied by publisher]
Publication date: Available online 29 March 2020Source: Trends in Food Science &TechnologyAuthor(s): Mohanambal Moorthy, Nathorn Chaiyakunapruk, Sabrina Anne Jacob, Uma D. Palanisamy
Publication date: Available online 28 March 2020Source: Trends in Food Science &TechnologyAuthor(s): Francisco J. Barba, Shahin Roohinejad, Kenji Ishikawa, Sze Ying Leong, Alaa El-Din A Bekhit, Jorge A. Saraiva, Nikolai Lebovka
CONCLUSIONS: SBS can be safely and effectively treated with EBD using BAE, thus reducing the need for surgery in the long term. PMID: 32216446 [PubMed - as supplied by publisher]
Authors: González-Suárez B, Giordano A, Llach J Abstract The Novel Motorized Spiral Enteroscope (PowerSpiral®, Olympus) (PSE) has been recently commercialized with promising results in relation to insertion depth and time of exploration. We herewith report our first case of a total small bowel exploration with PSE. PMID: 32216445 [PubMed - as supplied by publisher]
CONCLUSIONS: In overweight and obese subjects undergoing a Mediterranean-type low-calorie diet, a different distribution of daily protein intake between meals and snacks does not result in significant differences in terms of FM loss and LBM maintenance. This is one of the first studies showing that nutritional dietary plans with different daily protein distribution show no particular differences in fat loss and lean mass maintenance. PMID: 32218430 [PubMed - as supplied by publisher]
Authors: Testino G, Balbinot P, Leone S, Pellicano R PMID: 32218429 [PubMed - as supplied by publisher]
Authors: Leone S, Pellicano R, Testino G, Caputo F PMID: 32218428 [PubMed - as supplied by publisher]
Authors: Priora M, Realmuto C, Parisi S, Ditto MC, Borrelli R, Peroni CL, Laganà A, Fusaro E Abstract Beyond the classic hepatic complications, hepatitis C (HCV) infection is considered as a systemic disease, since extrahepatic manifestations become clinically evident in 40 to 70% of the patients and it can frequently include rheumatic ones. Furthermore, HCV can promote the production of several autoantibodies, thus complicating the differential diagnosis between primitive and HCV- related rheumatic disorders. The recent development of direct-acting antivirals (DAA) against HCV has revolutionized the field, ...
CONCLUSIONS: The correlation between increase of inflammatory markers and increased risk of osteoporotic fractures and the lack of difference between Crohn's disease and ulcerative colitis suggest a central role of inflammation over malabsorption in this population. PMID: 32218426 [PubMed - as supplied by publisher]