FDG-PET imaging in hematological malignancies
The majority of aggressive lymphomas is characterized by an up regulated glycolytic activity, which enables the visualization by F-18 FDG-PET/CT. One-stop hybrid FDG-PET/CT combines the functional and morphologic information, outperforming both, CT and FDG-PET as separate imaging modalities. This has resulted in several recommendations using FDG-PET/CT for staging, restaging, monitoring during therapy, and assessment of treatment response as well as identification of malignant transformation. FDG-PET/CT may obviate the need for a bone marrow biopsy in patients with Hodgkin's lymphoma and diffuse large B cell lymphoma.
Source: Blood Reviews - Category: Hematology Authors: L. Valls, C. Badve, S. Avril, K. Herrmann, P. Faulhaber, J. O'Donnell, N. Avril Tags: Review Source Type: research